Kara A. Scheibner, Ph.D.

Affiliations: 
2004 Johns Hopkins University, Baltimore, MD 
Area:
Pharmacology, Biochemistry, Medical Biophysics
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"Kara Scheibner"
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Parents

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Philip A. Cole grad student 2004 Johns Hopkins
 (Serotonin N-acetyltransferase: Filling in the mechanistic holes.)
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Publications

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Muvarak N, Kelley S, Robert C, et al. (2015) c-MYC Generates Repair Errors via Increased Transcription of Alternative-NHEJ Factors, LIG3 and PARP1, in Tyrosine Kinase-Activated Leukemias. Molecular Cancer Research : McR. 13: 699-712
Lee TY, Ezelle HJ, Venkataraman T, et al. (2013) Regulation of human RNase-L by the miR-29 family reveals a novel oncogenic role in chronic myelogenous leukemia. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 33: 34-42
Muvarak NE, Kelley SM, Tarasco M, et al. (2013) C-MYC and C-MYC-Regulated Micrornas Increase The Activity Of The Error-Prone ALT NHEJ Pathway Through Upregulation Of LIG3 and PARP1 In Tyrosine Kinase-Activated Leukemias Blood. 122: 809-809
Scheibner KA, Teaboldt B, Hauer MC, et al. (2012) MiR-27a functions as a tumor suppressor in acute leukemia by regulating 14-3-3θ. Plos One. 7: e50895
Hassel B, Hsi T, Ezelle H, et al. (2012) P140 MicroRNA-29 regulation of RNase-L reveals a novel function in oncogenesis Cytokine. 59: 565
Scheibner KA, Heiser D, Kaplan IM, et al. (2010) MicroRNA Maestros of Hematopoiesis Blood. 116: SCI-32-SCI-32
Scheibner KA, Teaboldt B, Hauer MC, et al. (2010) The Mir-23a∼Mir-27a∼Mir-24 Cluster Acts as a Tumor Suppressor In Leukemias by Post-Transcriptional Regulation of 14-3-3 Proteins Blood. 116: 3145-3145
Scheibner KA, Zhang Z, Cole PA. (2003) Merging fluorescence resonance energy transfer and expressed protein ligation to analyze protein-protein interactions. Analytical Biochemistry. 317: 226-32
Scheibner KA, De Angelis J, Burley SK, et al. (2002) Investigation of the roles of catalytic residues in serotonin N-acetyltransferase. The Journal of Biological Chemistry. 277: 18118-26
Zheng W, Scheibner KA, Ho AK, et al. (2001) Mechanistic studies on the alkyltransferase activity of serotonin N-acetyltransferase. Chemistry & Biology. 8: 379-89
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