Jayakrishnan Nandakumar, Ph.D.

2007 Weill Cornell Medical College, New York, NY, United States 
Biochemistry, Molecular Biology
"Jayakrishnan Nandakumar"
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Christopher D. Lima grad student 2007 Weill Cornell Medical College
 (Discrimination of RNA versus DNA by an RNA ligase, and, Distinct modes of substrate recognition by DNA ligases.)
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Tesmer VM, Brenner KA, Nandakumar J. (2023) Human POT1 protects the telomeric ds-ss DNA junction by capping the 5' end of the chromosome. Science (New York, N.Y.). 381: 771-778
Moritz L, Schon SB, Rabbani M, et al. (2023) Sperm chromatin structure and reproductive fitness are altered by substitution of a single amino acid in mouse protamine 1. Nature Structural & Molecular Biology
Padmanaban S, Tesmer VM, Nandakumar J. (2023) Interaction hub critical for telomerase recruitment and primer-template handling for catalysis. Life Science Alliance. 6
Wozniak KJ, Burby PE, Nandakumar J, et al. (2022) Structure and kinase activity of bacterial cell cycle regulator CcrZ. Plos Genetics. 18: e1010196
Brenner KA, Nandakumar J. (2022) Consequences of telomere replication failure: the other end-replication problem. Trends in Biochemical Sciences. 47: 506-517
Zhang K, Tarczykowska A, Gupta DK, et al. (2022) The TERB1 MYB domain suppresses telomere erosion in meiotic prophase I. Cell Reports. 38: 110289
Zhang J, Nandakumar J, Shibuya H. (2021) BRCA2 in mammalian meiosis. Trends in Cell Biology
Gu P, Jia S, Takasugi T, et al. (2021) Distinct functions of POT1 proteins contribute to the regulation of telomerase recruitment to telomeres. Nature Communications. 12: 5514
Pendlebury DF, Zhang J, Agrawal R, et al. (2021) Structure of a meiosis-specific complex central to BRCA2 localization at recombination sites. Nature Structural & Molecular Biology. 28: 671-680
Grill S, Padmanaban S, Friedman A, et al. (2021) TPP1 mutagenesis screens unravel shelterin interfaces and functions in hematopoiesis. Jci Insight
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