Jayakrishnan Nandakumar, Ph.D.

Affiliations: 
2007 Weill Cornell Medical College, New York, NY, United States 
Area:
Biochemistry, Molecular Biology
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"Jayakrishnan Nandakumar"
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Parents

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Christopher D. Lima grad student 2007 Weill Cornell Medical College
 (Discrimination of RNA versus DNA by an RNA ligase, and, Distinct modes of substrate recognition by DNA ligases.)
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Publications

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Manthei KA, Munson LM, Nandakumar J, et al. (2024) Structural and biochemical characterization of the mitomycin C repair exonuclease MrfB. Nucleic Acids Research
Padmanaban S, Lambacher NJ, Tesmer VM, et al. (2024) telomere-binding proteins TEBP-1 and TEBP-2 adapt the Myb module to dimerize and bind telomeric DNA. Proceedings of the National Academy of Sciences of the United States of America. 121: e2316651121
Manthei KA, Munson LM, Nandakumar J, et al. (2024) Structural and biochemical characterization of the mitomycin C repair exonuclease MrfB. Biorxiv : the Preprint Server For Biology
Tesmer VM, Brenner KA, Nandakumar J. (2023) Human POT1 protects the telomeric ds-ss DNA junction by capping the 5' end of the chromosome. Science (New York, N.Y.). 381: 771-778
Moritz L, Schon SB, Rabbani M, et al. (2023) Sperm chromatin structure and reproductive fitness are altered by substitution of a single amino acid in mouse protamine 1. Nature Structural & Molecular Biology
Padmanaban S, Tesmer VM, Nandakumar J. (2023) Interaction hub critical for telomerase recruitment and primer-template handling for catalysis. Life Science Alliance. 6
Wozniak KJ, Burby PE, Nandakumar J, et al. (2022) Structure and kinase activity of bacterial cell cycle regulator CcrZ. Plos Genetics. 18: e1010196
Brenner KA, Nandakumar J. (2022) Consequences of telomere replication failure: the other end-replication problem. Trends in Biochemical Sciences. 47: 506-517
Zhang K, Tarczykowska A, Gupta DK, et al. (2022) The TERB1 MYB domain suppresses telomere erosion in meiotic prophase I. Cell Reports. 38: 110289
Zhang J, Nandakumar J, Shibuya H. (2021) BRCA2 in mammalian meiosis. Trends in Cell Biology
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