Niroshika Keppetipola, Ph.D.

2009 Weill Cornell Medical College, New York, NY, United States 
Biochemistry, Molecular Biology
"Niroshika Keppetipola"
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Stewart Shuman grad student 2009 Weill Cornell Medical College
 (Characterization of DNA and RNA end modifying enzymes, and, A triphosphate tunnel metalloenzyme.)
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Ontiveros RJ, Hernandez L, Nguyen H, et al. (2020) Identification and Characterization of a Minimal Functional Splicing Regulatory Protein, PTBP1. Biochemistry
Pina JM, Reynaga JM, Truong AAM, et al. (2018) Post-Translational Modifications in Polypyrimidine Tract Binding Proteins PTBP1 and PTBP2. Biochemistry
Keppetipola NM, Yeom KH, Hernandez AL, et al. (2016) Multiple determinants of splicing repression activity in the polypyrimidine tract binding proteins, PTBP1 and PTBP2. Rna (New York, N.Y.)
Keppetipola N, Sharma S, Li Q, et al. (2012) Neuronal regulation of pre-mRNA splicing by polypyrimidine tract binding proteins, PTBP1 and PTBP2 Critical Reviews in Biochemistry and Molecular Biology. 47: 360-378
Keppetipola N, Jain R, Meineke B, et al. (2009) Structure-activity relationships in Kluyveromyces lactis γ-toxin, a eukaryal tRNA anticodon nuclease Rna. 15: 1036-1044
Keppetipola N, Shuman S. (2008) A phosphate-binding histidine of binuclear metallophosphodiesterase enzymes is a determinant of 2',3'-cyclic nucleotide phosphodiesterase activity. The Journal of Biological Chemistry. 283: 30942-9
Keppetipola N, Shuman S. (2007) Characterization of the 2',3' cyclic phosphodiesterase activities of Clostridium thermocellum polynucleotide kinase-phosphatase and bacteriophage lambda phosphatase. Nucleic Acids Research. 35: 7721-32
Keppetipola N, Nandakumar J, Shuman S. (2007) Reprogramming the tRNA-splicing activity of a bacterial RNA repair enzyme. Nucleic Acids Research. 35: 3624-30
Keppetipola N, Jain R, Shuman S. (2007) Novel triphosphate phosphohydrolase activity of Clostridium thermocellum TTM, a member of the triphosphate tunnel metalloenzyme superfamily. The Journal of Biological Chemistry. 282: 11941-9
Keppetipola N, Shuman S. (2006) Distinct enzymic functional groups are required for the phosphomonoesterase and phosphodiesterase activities of Clostridium thermocellum polynucleotide kinase/phosphatase. The Journal of Biological Chemistry. 281: 19251-9
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