Simon WM John, P.h.D.

Affiliations: 
The Jackson Laboratory, Bar Harbor, ME, United States 
Area:
Glaucoma, genetics
Website:
http://www.simonjohnlab.org/dr-simon-wm-john
Google:
"Simon John"
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Parents

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Rima Rozen grad student 1992 McGill (Cell Biology Tree)
Charles R. Scriver grad student 1992 McGill
Oliver Smithies post-doc 1995 NCSU

Children

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Douglas Gould post-doc 2006 The Jackson Laboratory (Cell Biology Tree)
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Publications

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Harder JM, Braine CE, Williams PA, et al. (2017) Early immune responses are independent of RGC dysfunction in glaucoma with complement component C3 being protective. Proceedings of the National Academy of Sciences of the United States of America
Williams PA, Harder JM, Foxworth NE, et al. (2017) Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice. Science (New York, N.Y.). 355: 756-760
Nair KS, Cosma M, Raghupathy N, et al. (2016) YBR/EiJ mice: a new model of glaucoma caused by genes on chromosomes 4 and 17. Disease Models & Mechanisms
Souma T, Tompson SW, Thomson BR, et al. (2016) Angiopoietin receptor TEK mutations underlie primary congenital glaucoma with variable expressivity. The Journal of Clinical Investigation
Williams PA, Tribble JR, Pepper KW, et al. (2016) Inhibition of the classical pathway of the complement cascade prevents early dendritic and synaptic degeneration in glaucoma. Molecular Neurodegeneration. 11: 26
Silverman SM, Kim BJ, Howell GR, et al. (2016) C1q propagates microglial activation and neurodegeneration in the visual axis following retinal ischemia/reperfusion injury. Molecular Neurodegeneration. 11: 24
Alavi MV, Mao M, Pawlikowski BT, et al. (2016) Col4a1 mutations cause progressive retinal neovascular defects and retinopathy. Scientific Reports. 6: 18602
Mao M, Smith RS, Alavi MV, et al. (2015) Strain-Dependent Anterior Segment Dysgenesis and Progression to Glaucoma in Col4a1 Mutant Mice. Investigative Ophthalmology & Visual Science. 56: 6823-6831
Lee ST, Williams PA, Braine CE, et al. (2015) A Miniature, Fiber-Coupled, Wireless, Deep-Brain Optogenetic Stimulator. Ieee Transactions On Neural Systems and Rehabilitation Engineering : a Publication of the Ieee Engineering in Medicine and Biology Society. 23: 655-64
Ward MP, Qing KY, Otto KJ, et al. (2015) A flexible platform for biofeedback-driven control and personalization of electrical nerve stimulation therapy. Ieee Transactions On Neural Systems and Rehabilitation Engineering : a Publication of the Ieee Engineering in Medicine and Biology Society. 23: 475-84
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