Simon WM John, P.h.D.
Affiliations: | The Jackson Laboratory, Bar Harbor, ME, United States |
Area:
Glaucoma, geneticsWebsite:
http://www.simonjohnlab.org/dr-simon-wm-johnGoogle:
"Simon John"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Rima Rozen | grad student | 1992 | McGill (Cell Biology Tree) |
| Charles R. Scriver | grad student | 1992 | McGill |
| Oliver Smithies | post-doc | 1995 | NCSU |
Children
Sign in to add trainee| Douglas Gould | post-doc | 2006 | The Jackson Laboratory (Cell Biology Tree) |
BETA: Related publications
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Publications
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| Paylakhi S, Labelle-Dumais C, Tolman NG, et al. (2018) Müller glia-derived PRSS56 is required to sustain ocular axial growth and prevent refractive error. Plos Genetics. 14: e1007244 |
| Thomson BR, Souma T, Tompson SW, et al. (2017) Angiopoietin-1 is required for Schlemm's canal development in mice and humans. The Journal of Clinical Investigation |
| Williams PA, Harder JM, Foxworth NE, et al. (2017) Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice. Science (New York, N.Y.). 355: 756-760 |
| Nair KS, Cosma M, Raghupathy N, et al. (2016) YBR/EiJ mice: a new model of glaucoma caused by genes on chromosomes 4 and 17. Disease Models & Mechanisms |
| Souma T, Tompson SW, Thomson BR, et al. (2016) Angiopoietin receptor TEK mutations underlie primary congenital glaucoma with variable expressivity. The Journal of Clinical Investigation |
| Alavi MV, Mao M, Pawlikowski BT, et al. (2016) Col4a1 mutations cause progressive retinal neovascular defects and retinopathy. Scientific Reports. 6: 18602 |
| Mao M, Smith RS, Alavi MV, et al. (2015) Strain-Dependent Anterior Segment Dysgenesis and Progression to Glaucoma in Col4a1 Mutant Mice. Investigative Ophthalmology & Visual Science. 56: 6823-6831 |
| Fernandes KA, Harder JM, Williams PA, et al. (2015) Using genetic mouse models to gain insight into glaucoma: Past results and future possibilities. Experimental Eye Research |
| Cross SH, Macalinao DG, McKie L, et al. (2014) A dominant-negative mutation of mouse Lmx1b causes glaucoma and is semi-lethal via LBD1-mediated dimerisation. Plos Genetics. 10: e1004359 |
| Nair KS, Hmani-Aifa M, Ali Z, et al. (2011) Alteration of the serine protease PRSS56 causes angle-closure glaucoma in mice and posterior microphthalmia in humans and mice. Nature Genetics. 43: 579-84 |