Brian R. Chapados, Ph.D.
Affiliations: | 2005 | Scripps Research Institute, La Jolla, La Jolla, CA, United States |
Area:
Biochemistry, General Biophysics, Molecular BiologyGoogle:
"Brian Chapados"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| John Tainer | grad student | 2005 | Scripps Institute | |
| (Substrate recognition and regulation of structure -specific nucleases central to DNA replication and repair.) | ||||
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Publications
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| Tsutakawa SE, Classen S, Chapados BR, et al. (2011) Human flap endonuclease structures, DNA double-base flipping, and a unified understanding of the FEN1 superfamily. Cell. 145: 198-211 |
| Zeitlin SG, Chapados BR, Baker NM, et al. (2011) Uracil DNA N-glycosylase promotes assembly of human centromere protein A. Plos One. 6: e17151 |
| Tomlinson CG, Atack JM, Chapados B, et al. (2010) Substrate recognition and catalysis by flap endonucleases and related enzymes Biochemical Society Transactions. 38: 433-437 |
| Zeitlin SG, Baker NM, Chapados BR, et al. (2009) Double-strand DNA breaks recruit the centromeric histone CENP-A. Proceedings of the National Academy of Sciences of the United States of America. 106: 15762-7 |
| Syson K, Tomlinson C, Chapados BR, et al. (2008) Three metal ions participate in the reaction catalyzed by T5 flap endonuclease. The Journal of Biological Chemistry. 283: 28741-6 |
| Williams R, Sengerová B, Osborne S, et al. (2007) Comparison of the catalytic parameters and reaction specificities of a phage and an archaeal flap endonuclease. Journal of Molecular Biology. 371: 34-48 |
| Vijayakumar S, Chapados BR, Schmidt KH, et al. (2007) The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase Nucleic Acids Research. 35: 1624-1637 |
| Ivanov I, Chapados BR, McCammon JA, et al. (2006) Proliferating cell nuclear antigen loaded onto double-stranded DNA: dynamics, minor groove interactions and functional implications. Nucleic Acids Research. 34: 6023-33 |
| Chao JA, Lee JH, Chapados BR, et al. (2005) Dual modes of RNA-silencing suppression by Flock House virus protein B2. Nature Structural & Molecular Biology. 12: 952-7 |
| Qiu J, Liu R, Chapados BR, et al. (2004) Interaction interface of human flap endonuclease-1 with its DNA substrates. The Journal of Biological Chemistry. 279: 24394-402 |