Jason C. Choi, Ph.D.
Affiliations: | 2007 | Roswell Park - Microbiology and Immunology | State University of New York, Buffalo, Buffalo, NY, United States |
Area:
Immunology, Molecular BiologyGoogle:
"Jason Choi"Parents
Sign in to add mentorHoward J Worman | grad student | Thomas Jefferson (Cell Biology Tree) | ||
Shawn P. Murphy | grad student | 2007 | SUNY Buffalo | |
(Regulation of interferon-gamma signal transduction in human and mouse trophoblast cells.) |
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Publications
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Sikder K, Phillips E, Zhong Z, et al. (2023) Perinuclear damage from nuclear envelope deterioration elicits stress responses that contribute to cardiomyopathy. Biorxiv : the Preprint Server For Biology |
Sikder K, Phillips E, Zhong Z, et al. (2019) Abstract 730: Celltype-Specific Functions in Dilated Cardiomyopathy Caused by the LMNA Gene Mutation Circulation Research. 125 |
Choi JC, Wu W, Phillips E, et al. (2018) Elevated dual specificity protein phosphatase 4 in cardiomyopathy caused by lamin A/C gene mutation is primarily ERK1/2-dependent and its depletion improves cardiac function and survival. Human Molecular Genetics |
Choi JC, Worman HJ. (2014) Nuclear envelope regulation of signaling cascades. Advances in Experimental Medicine and Biology. 773: 187-206 |
Muchir A, Kim YJ, Reilly SA, et al. (2013) Inhibition of extracellular signal-regulated kinase 1/2 signaling has beneficial effects on skeletal muscle in a mouse model of Emery-Dreifuss muscular dystrophy caused by lamin A/C gene mutation. Skeletal Muscle. 3: 17 |
Choi JC, Worman HJ. (2013) Reactivation of autophagy ameliorates LMNA cardiomyopathy. Autophagy. 9: 110-1 |
Choi JC, Wu W, Muchir A, et al. (2012) Dual specificity phosphatase 4 mediates cardiomyopathy caused by lamin A/C (LMNA) gene mutation. The Journal of Biological Chemistry. 287: 40513-24 |
Wang Y, Ostlund C, Choi JC, et al. (2012) Blocking farnesylation of the prelamin A variant in Hutchinson-Gilford progeria syndrome alters the distribution of A-type lamins. Nucleus (Austin, Tex.). 3: 452-62 |
Choi JC, Muchir A, Wu W, et al. (2012) Temsirolimus activates autophagy and ameliorates cardiomyopathy caused by lamin A/C gene mutation. Science Translational Medicine. 4: 144ra102 |
Muchir A, Wu W, Choi JC, et al. (2012) Abnormal p38α mitogen-activated protein kinase signaling in dilated cardiomyopathy caused by lamin A/C gene mutation. Human Molecular Genetics. 21: 4325-33 |