Ravi Rai, Ph.D.

Affiliations: 
2006 Utah State University, Logan, UT, United States 
Area:
Organic Chemistry
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Cheng-Wei Tom Chang grad student 2006 Utah State University
 (Design and synthesis of novel aminoglycosides with activity against modifying enzymes.)
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Publications

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Udumula V, Ham YW, Fosso MY, et al. (2013) Investigation of antibacterial mode of action for traditional and amphiphilic aminoglycosides. Bioorganic & Medicinal Chemistry Letters. 23: 1671-5
Zhang J, Litke A, Keller K, et al. (2010) Synthesis of novel aminoglycosides via allylic azide rearrangement for investigating the significance of 2'-amino group. Bioorganic & Medicinal Chemistry. 18: 1396-405
Mattis VB, Rai R, Wang J, et al. (2006) Novel aminoglycosides increase SMN levels in spinal muscular atrophy fibroblasts. Human Genetics. 120: 589-601
Rai R, Chen HN, Czyryca PG, et al. (2006) Design and synthesis of pyrankacin: a pyranmycin class of broad-spectrum aminoglycoside antibiotic. Organic Letters. 8: 887-9
Rai R, Chen H, Chang H, et al. (2005) Novel Method for the Synthesis of 3′,4′‐Dideoxygenated Pyranmycin and Kanamycin Compounds, and Studies of Their Antibacterial Activity Against Aminoglycoside‐Resistant Bacteria Journal of Carbohydrate Chemistry. 24: 131-143
Rai R, McAlexander I, Chang CT. (2005) SYNTHETIC GLYCODIVERSIFICATION. FROM AMINOSUGARS TO AMINOGLYCOSIDE ANTIBIOTICS. A REVIEW Organic Preparations and Procedures International. 37: 337-375
Rai R, Chen H, Chang H, et al. (2005) Novel Method for the Synthesis of 3′,4′-Dideoxygenated Pyranmycin and Kanamycin Compounds, and Studies of Their Antibacterial Activity Against Aminoglycoside-Resistant Bacteria. Cheminform. 36
Wang J, Elchert B, Hui Y, et al. (2004) Synthesis of trehalose-based compounds and their inhibitory activities against Mycobacterium smegmatis. Bioorganic & Medicinal Chemistry. 12: 6397-413
Elchert B, Li J, Wang J, et al. (2004) Application of the synthetic aminosugars for glycodiversification: synthesis and antimicrobial studies of pyranmycin. The Journal of Organic Chemistry. 69: 1513-23
Chang CW, Hui Y, Elchert B, et al. (2002) Pyranmycins, a novel class of aminoglycosides with improved acid stability: the SAR of D-pyranoses on ring III of pyranmycin. Organic Letters. 4: 4603-6
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