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Todd A. Lydic, Ph.D.

Affiliations: 
2012 Physiology Michigan State University, East Lansing, MI 
Area:
Physiology Biology, Analytical Chemistry, Biochemistry
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Julia V. Busik grad student 2012 Michigan State
 (A lipidomics study of diabetic retinopathy reveals a novel role for fatty acid elongase ELOVL4 in the maintenance of retinal vascular integrity.)

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Beli E, Yan Y, Moldovan L, et al. (2025) Reshaping lipid metabolism with long-term alternate day feeding in type 2 diabetes mice. Npj Metabolic Health and Disease. 3: 3
Dorweiler TF, Singh A, Ganju A, et al. (2024) Diabetic retinopathy is a ceramidopathy reversible by anti-ceramide immunotherapy. Cell Metabolism
Kostina A, Lewis-Israeli YR, Abdelhamid M, et al. (2024) ER stress and lipid imbalance drive diabetic embryonic cardiomyopathy in an organoid model of human heart development. Stem Cell Reports
Ahmad Z, Singh S, Lee TJ, et al. (2024) Untargeted and temporal analysis of retinal lipidome in bacterial endophthalmitis. Prostaglandins & Other Lipid Mediators. 106806
Kostina A, Lewis-Israeli YR, Abdelhamid M, et al. (2023) ER stress and lipid imbalance drive embryonic cardiomyopathy in a human heart organoid model of pregestational diabetes. Biorxiv : the Preprint Server For Biology
Busik JV, Decot H, Lin AB, et al. (2023) Untargeted Analysis of Lipids Containing Very Long Chain Fatty Acids in Retina and Retinal Tight Junctions. Methods in Molecular Biology (Clifton, N.J.). 2625: 269-290
Lydic TA, Busik JV. (2022) Diabetes Retinopathy: New Ways to Detect and Treat. Methods in Molecular Biology (Clifton, N.J.). 2592: 89-100
Hammer SS, Vieira CP, McFarland D, et al. (2021) Fasting and fasting-mimicking treatment activate SIRT1/LXRα and alleviate diabetes-induced systemic and microvascular dysfunction. Diabetologia
Vieira CP, Fortmann SD, Hossain M, et al. (2020) Selective LXR agonist DMHCA corrects retinal and bone marrow dysfunction in type 2 diabetes. Jci Insight. 5
Truong NTT, Lydic TA, Bazil JN, et al. (2020) Regulation of lipid metabolism in pancreatic beta cells by interferon gamma: A link to anti-viral function. Cytokine. 133: 155147
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