Nathan A. Schnarr

Chemistry University of Massachusetts, Amherst, Amherst, MA 
General Chemistry, Biochemistry
"Nathan A Schnarr"

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Alan J. Kennan grad student 2004 Colorado State
 (Specific coiled coil assembly through size-complementarity.)
Chaitan Khosla post-doc 2004-2007 Stanford
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Gann AW, Amoroso JW, Einck VJ, et al. (2014) A photoinduced, benzyne click reaction. Organic Letters. 16: 2003-5
Lin TY, Borketey LS, Prasad G, et al. (2013) Sequence, cloning, and analysis of the fluvirucin B1 polyketide synthase from Actinomadura vulgaris. Acs Synthetic Biology. 2: 635-42
Prasad G, Borketey LS, Lin TY, et al. (2012) A mechanism-based fluorescence transfer assay for examining ketosynthase selectivity. Organic & Biomolecular Chemistry. 10: 6717-23
Prasad G, Amoroso JW, Borketey LS, et al. (2012) N-activated β-lactams as versatile reagents for acyl carrier protein labeling. Organic & Biomolecular Chemistry. 10: 1992-2002
Amoroso JW, Borketey LS, Prasad G, et al. (2010) Direct acylation of carrier proteins with functionalized beta-lactones. Organic Letters. 12: 2330-3
Schnarr NA, Khosla C. (2008) Diversity-oriented Synthesis: Combinatorial Biosynthesis of Polyketides and Nonribosomal Peptides Chemical Biology: From Small Molecules to Systems Biology and Drug Design, Volume 1-3. 2: 519-536
Khosla C, Tang Y, Chen AY, et al. (2007) Structure and mechanism of the 6-deoxyerythronolide B synthase. Annual Review of Biochemistry. 76: 195-221
Schnarr NA, Khosla C. (2006) Trapping transient protein-protein interactions in polyketide biosynthesis. Acs Chemical Biology. 1: 679-80
Hicks LM, Mazur MT, Miller LM, et al. (2006) Investigating nonribosomal peptide and polyketide biosynthesis by direct detection of intermediates on >70 kDa polypeptides by using Fourier-transform mass spectrometry. Chembiochem : a European Journal of Chemical Biology. 7: 904-7
Chen AY, Schnarr NA, Kim CY, et al. (2006) Extender unit and acyl carrier protein specificity of ketosynthase domains of the 6-deoxyerythronolide B synthase. Journal of the American Chemical Society. 128: 3067-74
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