Piotr K. Grzyska, Ph.D.

Affiliations: 
2003 Utah State University, Logan, UT, United States 
Area:
Organic Chemistry
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"Piotr Grzyska"
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Parents

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Alvan C. Hengge grad student 2003 Utah State University
 (Insights on enzymatic and uncatalyzed phosphoryl transfer.)
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Publications

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Casey TM, Grzyska PK, Hausinger RP, et al. (2013) Measuring the orientation of taurine in the active site of the non-heme Fe(II)/α-ketoglutarate-dependent taurine hydroxylase (TauD) using electron spin echo envelope modulation (ESEEM) spectroscopy. The Journal of Physical Chemistry. B. 117: 10384-94
Grzyska PK, Appelman EH, Hausinger RP, et al. (2010) Insight into the mechanism of an iron dioxygenase by resolution of steps following the FeIV=HO species. Proceedings of the National Academy of Sciences of the United States of America. 107: 3982-7
Grzyska PK, Hausinger RP, Proshlyakov DA. (2010) Metal and substrate binding to an Fe(II) dioxygenase resolved by UV spectroscopy with global regression analysis. Analytical Biochemistry. 399: 64-71
Grzyska PK, Hausinger RP. (2007) Cr(II) reactivity of taurine/alpha-ketoglutarate dioxygenase. Inorganic Chemistry. 46: 10087-92
Zalatan JG, Catrina I, Mitchell R, et al. (2007) Kinetic isotope effects for alkaline phosphatase reactions: implications for the role of active-site metal ions in catalysis. Journal of the American Chemical Society. 129: 9789-98
Muthukumaran RB, Grzyska PK, Hausinger RP, et al. (2007) Probing the iron-substrate orientation for taurine/alpha-ketoglutarate dioxygenase using deuterium electron spin echo envelope modulation spectroscopy. Biochemistry. 46: 5951-9
Grzyska PK, Müller TA, Campbell MG, et al. (2007) Metal ligand substitution and evidence for quinone formation in taurine/alpha-ketoglutarate dioxygenase. Journal of Inorganic Biochemistry. 101: 797-808
Grzyska PK, Czyryca PG, Purcell J, et al. (2007) Transition State Differences in Hydrolysis Reactions of Alkyl versus Aryl Phosphate Monoester Monoanions [J. Am. Chem. Soc.2003,125, 13106−13111]. Journal of the American Chemical Society. 129: 5298-5298
Luo L, Pappalardi MB, Tummino PJ, et al. (2006) An assay for Fe(II)/2-oxoglutarate-dependent dioxygenases by enzyme-coupled detection of succinate formation. Analytical Biochemistry. 353: 69-74
Kalliri E, Grzyska PK, Hausinger RP. (2005) Kinetic and spectroscopic investigation of CoII, NiII, and N-oxalylglycine inhibition of the FeII/alpha-ketoglutarate dioxygenase, TauD. Biochemical and Biophysical Research Communications. 338: 191-7
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