Theresa Downey, Ph.D.
Affiliations: | 2014 | Pharmaceutical Sciences | University of Kentucky, Lexington, KY |
Area:
Pharmacy, BiochemistryGoogle:
"Theresa Downey"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Jurgen Rohr | grad student | 2014 | University of Kentucky | |
| (Investigating structure and protein-protein interactions of key post-type ii pks tailoring enzymes.) | ||||
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| Panchuk RR, Lehka LV, Terenzi A, et al. (2017) Rapid generation of hydrogen peroxide contributes to the complex cell death induction by the angucycline antibiotic landomycin E. Free Radical Biology & Medicine |
| Bosserman MA, Downey T, Noinaj N, et al. (2013) Molecular insight into substrate recognition and catalysis of Baeyer-Villiger monooxygenase MtmOIV, the key frame-modifying enzyme in the biosynthesis of anticancer agent mithramycin. Acs Chemical Biology. 8: 2466-77 |
| Downey T, Bosserman M, Noinaj N, et al. (2013) Investigating and Re-Engineering Baeyer-Villiger Monooxygenase MtmOIV for Combinatorial Biosynthesis of Novel Aureolic Acid Anticancer Drug Analogues Planta Medica. 79 |
| Tibrewal N, Pahari P, Wang G, et al. (2012) Baeyer-Villiger C-C bond cleavage reaction in gilvocarcin and jadomycin biosynthesis. Journal of the American Chemical Society. 134: 18181-4 |
| Tibrewal N, Downey TE, Van Lanen SG, et al. (2012) Roles of the synergistic reductive O-methyltransferase GilM and of O-methyltransferase GilMT in the gilvocarcin biosynthetic pathway. Journal of the American Chemical Society. 134: 12402-5 |
| Tibrewal N, Downey T, Rohr J. (2012) Synergistic reductive methyltransferase GILM and its crucial role in gilvocarcin biosynthetic pathway Planta Medica. 78 |