Aimee K. Bence, Ph.D.

Affiliations: 
2001 University of Kentucky, Lexington, KY 
Area:
Pharmacology
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Peter A. Crooks grad student 2001 University of Kentucky
 (Evaluation of L-canavanine, L-indospicine and other L-arginine analogs as potential therapeutics in the treatment of pancreatic cancer.)
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Publications

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Bence AK, Crooks PA. (2010) ChemInform Abstract: Synthesis of L-Indospicine. Cheminform. 33: no-no
Worthen DR, Bence AK, Stables JP, et al. (2009) In vivo evaluation of diaminodiphenyls: anticonvulsant agents with minimal acute neurotoxicity. Bioorganic & Medicinal Chemistry Letters. 19: 5012-5
Bence AK, Crooks PA. (2003) The mechanism of L-canavanine cytotoxicity: arginyl tRNA synthetase as a novel target for anticancer drug discovery. Journal of Enzyme Inhibition and Medicinal Chemistry. 18: 383-94
Bence AK, Adams VR, Crooks PA. (2003) L-Canavanine as a radiosensitization agent for human pancreatic cancer cells. Molecular and Cellular Biochemistry. 244: 37-43
Bence AK, Worthen DR, Stables JP, et al. (2003) An in vivo evaluation of the antiseizure activity and acute neurotoxicity of agmatine. Pharmacology, Biochemistry, and Behavior. 74: 771-5
Bence AK, Worthen DR, Adams VR, et al. (2002) The antiproliferative and immunotoxic effects of L-canavanine and L-canaline. Anti-Cancer Drugs. 13: 313-20
Bence AK, Crooks PA. (2002) Synthesis of L-indospicine Synthetic Communications. 32: 2075-2082
Worthen DR, Gibson DA, Rogers DT, et al. (2001) Endogenous indoles as novel polyamine site ligands at the N-methyl-D-aspartate receptor complex. Brain Research. 890: 343-6
Bence AK, Rogers DT, Worthen DR, et al. (2000) Aminoanthraquinones as novel ligands at the polyamine binding site on the N-methyl-D-aspartate receptor complex. Bioorganic & Medicinal Chemistry Letters. 10: 2621-3
Bence AK, Rogers DT, Worthen DR, et al. (2000) Dapsone analogs as potential polyamine binding site modulators of the N-methyl-D-aspartate receptor complex Drug Development Research. 51: 268-272
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