Cara J. Gottardi, Ph.D.

Affiliations: 
2004- Driskill Graduate Program in the Life Sciences Northwestern University, Evanston, IL 
Area:
Cell-cell adhesion and signaling
Website:
https://caragottardilab.weebly.com/
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"Cara Gottardi"
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Parents

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Barry M. Gumbiner post-doc 1995-2002 UVA
 (Sloan-Kettering Research Institute)
Michael J. Caplan research scientist 1989-1993 Yale

Children

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Meghan T. Maher grad student 2005-2009 Washington University
Rebecca Daugherty grad student 2006-2011 Northwestern
Abbye E. McEwen grad student 2010-2014 University of Washington
David J. Escobar grad student 2010-2015 Northwestern
Stephen Sai Folmsbee grad student 2012-2016 Northwestern School of Medicine
Megan Novak Wood grad student 2013-2017 Northwestern
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Publications

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Wang Y, Yemelyanov A, Go CD, et al. (2025) α-Catenin force-sensitive binding and sequestration of LZTS2 leads to cytokinesis failure. The Journal of Cell Biology. 224
Le PM, Quinn JM, Flozak AS, et al. (2025) α-catenin phosphorylation is elevated during mitosis to resist apical rounding and epithelial barrier leak. Biology Open. 14
Le PM, Quinn JM, Steffeck AW, et al. (2024) α-catenin phosphorylation is elevated during mitosis to resist apical rounding and epithelial barrier leak. Biorxiv : the Preprint Server For Biology
Quinn JM, Wang Y, Wood M, et al. (2024) α-catenin middle- and actin-binding domain unfolding mutants differentially impact epithelial strength and sheet migration. Molecular Biology of the Cell. mbcE23010036
Gottardi CJ, Luxton GWG. (2020) Nesprin-2G tension fine-tunes Wnt/β-catenin signaling. The Journal of Cell Biology. 219
Shigemura M, Lecuona E, Angulo M, et al. (2019) Elevated CO regulates the Wnt signaling pathway in mammals, Drosophila melanogaster and Caenorhabditis elegans. Scientific Reports. 9: 18251
Malsin ES, Kim S, Lam AP, et al. (2019) Macrophages as a Source and Recipient of Wnt Signals. Frontiers in Immunology. 10: 1813
Ishiyama N, Sarpal R, Wood MN, et al. (2018) Force-dependent allostery of the α-catenin actin-binding domain controls adherens junction dynamics and functions. Nature Communications. 9: 5121
Chiarella SE, Rabin EE, Ostilla LA, et al. (2018) αT-catenin: A developmentally dispensable, disease-linked member of the α-catenin family. Tissue Barriers. e1463896
Ishiyama N, Sarpal R, Wood MN, et al. (2018) Force-dependent allostery of the alpha-catenin actin-binding domain controls adherens junction dynamics and functions. Nature Communications. 9: 5121-5121
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