David K. Cortez
Affiliations: | Biochemistry | Vanderbilt University, Nashville, TN |
Area:
Biochemistry, Molecular Biology, Cell BiologyWebsite:
https://medschool.vanderbilt.edu/biochemistry/person/david-k-cortez/Google:
"David Kenneth Cortez"Bio:
https://wag.app.vanderbilt.edu/PublicPage/Faculty/Details/30706
https://lab.vanderbilt.edu/cortez-lab/
https://lab.vanderbilt.edu/cortez-lab/people/
https://books.google.com/books?id=JosvAQAAIAAJ
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Parents
Sign in to add mentor| Ann M. Pendergast | grad student | 1997 | Duke (Neurotree) | |
| (Signaling by the Bcr-Abl tyrosine kinase.) | ||||
| Stephen J. Elledge | post-doc | 2002 | Baylor College of Medicine | |
Children
Sign in to add trainee| Daniel A. Mordes | grad student | 2008 | Vanderbilt |
| Courtney A. Lovejoy | grad student | 2009 | Vanderbilt |
| Sarah R. Wessel | post-doc | Vanderbilt |
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Publications
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| Lovejoy CA, Wessel SR, Bhowmick R, et al. (2025) SRBD1 facilitates chromosome segregation by promoting topoisomerase IIα localization to mitotic chromosomes. Nature Communications. 16: 1675 |
| Cranford MT, Dahmen SN, Cortez D, et al. (2025) Leading and lagging strand abasic sites differentially affect vertebrate replisome progression but involve analogous bypass mechanisms. Biorxiv : the Preprint Server For Biology |
| Cordero C, Mehta KPM, Weaver TM, et al. (2024) Contributing factors to the oxidation-induced mutational landscape in human cells. Nature Communications. 15: 10722 |
| Adolph MB, Warren GM, Couch FB, et al. (2024) Strand dependent bypass of DNA lesions during fork reversal by ATP-dependent translocases SMARCAL1, ZRANB3, and HLTF. Biorxiv : the Preprint Server For Biology |
| Bai G, Endres T, Kühbacher U, et al. (2024) HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stability. Molecular Cell |
| Adolph MB, Cortez D. (2024) Mechanisms and regulation of replication fork reversal. Dna Repair. 141: 103731 |
| Balakrishnan S, Adolph M, Tsai MS, et al. (2024) Structure of RADX and mechanism for regulation of RAD51 nucleofilaments. Proceedings of the National Academy of Sciences of the United States of America. 121: e2316491121 |
| Rua-Fernandez J, Lovejoy CA, Mehta KPM, et al. (2023) Self-reversal facilitates the resolution of HMCES DNA-protein crosslinks in cells. Cell Reports. 42: 113427 |
| Balakrishnan S, Adolph M, Tsai MS, et al. (2023) Structure of RADX and mechanism for regulation of RAD51 nucleofilaments. Biorxiv : the Preprint Server For Biology |
| Adolph MB, Garje AS, Balakrishnan S, et al. (2023) CRISPR-dependent Base Editing Screens Identify Separation of Function Mutants of RADX with Altered RAD51 Regulatory Activity. Journal of Molecular Biology. 435: 168236 |