David K. Cortez
Affiliations: | Biochemistry | Vanderbilt University, Nashville, TN |
Area:
Biochemistry, Molecular Biology, Cell BiologyWebsite:
https://medschool.vanderbilt.edu/biochemistry/person/david-k-cortez/Google:
"David Kenneth Cortez"Bio:
https://wag.app.vanderbilt.edu/PublicPage/Faculty/Details/30706
https://lab.vanderbilt.edu/cortez-lab/
https://lab.vanderbilt.edu/cortez-lab/people/
https://books.google.com/books?id=JosvAQAAIAAJ
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Parents
Sign in to add mentor| Ann M. Pendergast | grad student | 1997 | Duke (Neurotree) | |
| (Signaling by the Bcr-Abl tyrosine kinase.) | ||||
| Stephen J. Elledge | post-doc | 2002 | Baylor College of Medicine | |
Children
Sign in to add trainee| Daniel A. Mordes | grad student | 2008 | Vanderbilt |
| Courtney A. Lovejoy | grad student | 2009 | Vanderbilt |
| Sarah R. Wessel | post-doc | Vanderbilt |
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Publications
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| Balakrishnan S, Adolph M, Tsai MS, et al. (2023) Structure of RADX and mechanism for regulation of RAD51 nucleofilaments. Biorxiv : the Preprint Server For Biology |
| Adolph MB, Garje AS, Balakrishnan S, et al. (2023) CRISPR-dependent Base Editing Screens Identify Separation of Function Mutants of RADX with Altered RAD51 Regulatory Activity. Journal of Molecular Biology. 435: 168236 |
| Rua-Fernandez J, Lovejoy CA, Mehta KPM, et al. (2023) Self-reversal facilitates the resolution of HMCES-DNA protein crosslinks in cells. Biorxiv : the Preprint Server For Biology |
| Bhowmick R, Mehta KPM, Lerdrup M, et al. (2023) Integrator facilitates RNAPII removal to prevent transcription-replication collisions and genome instability. Molecular Cell |
| Liu W, Saito Y, Jackson J, et al. (2023) RAD51 bypasses the CMG helicase to promote replication fork reversal. Science (New York, N.Y.). 380: 382-387 |
| Kavlashvili T, Liu W, Mohamed TM, et al. (2023) Replication fork uncoupling causes nascent strand degradation and fork reversal. Nature Structural & Molecular Biology |
| Paulin KA, Cortez D, Eichman BF. (2022) The SOS response-associated peptidase (SRAP) domain of YedK catalyzes ring opening of abasic sites and reversal of its DNA-protein crosslink. The Journal of Biological Chemistry. 102307 |
| Van Ravenstein SX, Mehta KP, Kavlashvili T, et al. (2022) Topoisomerase II poisons inhibit vertebrate DNA replication through distinct mechanisms. The Embo Journal. e110632 |
| Mehta KPM, Thada V, Zhao R, et al. (2022) CHK1 phosphorylates PRIMPOL to promote replication stress tolerance. Science Advances. 8: eabm0314 |
| Mohamed T, Adolph MB, Cortez D. (2022) Oligomerization of DNA replication regulatory protein RADX is essential to maintain replication fork stability. The Journal of Biological Chemistry. 298: 101672 |