Julio A. Copello

Pharmacology Southern Illinois University at Carbondale, Carbondale, IL 
Pharmaceutical Chemistry
"Julio Copello"
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Darcy YL, Diaz-Sylvester PL, Copello JA. (2016) K201 (JTV519) is a Ca2+ dependent blocker of SERCA and a partial agonist of ryanodine receptors in striated muscle. Molecular Pharmacology
Diaz-Sylvester PL, Porta M, Juettner VV, et al. (2014) Eudistomin D and penaresin derivatives as modulators of ryanodine receptor channels and sarcoplasmic reticulum Ca2+ ATPase in striated muscle. Molecular Pharmacology. 85: 564-75
Porta M, Diaz-Sylvester PL, Neumann JT, et al. (2012) Coupled gating of skeletal muscle ryanodine receptors is modulated by Ca2+, Mg2+, and ATP. American Journal of Physiology. Cell Physiology. 303: C682-97
Diaz-Sylvester PL, Porta M, Copello JA. (2011) Modulation of cardiac ryanodine receptor channels by alkaline earth cations. Plos One. 6: e26693
Neumann JT, Copello JA. (2011) Cross-reactivity of ryanodine receptors with plasma membrane ion channel modulators. Molecular Pharmacology. 80: 509-17
Porta M, Zima AV, Nani A, et al. (2011) Single ryanodine receptor channel basis of caffeine's action on Ca2+ sparks. Biophysical Journal. 100: 931-8
Neumann JT, Diaz-Sylvester PL, Fleischer S, et al. (2011) CGP-37157 inhibits the sarcoplasmic reticulum Ca²+ ATPase and activates ryanodine receptor channels in striated muscle. Molecular Pharmacology. 79: 141-7
Ramos-Franco J, Gomez AM, Nani A, et al. (2010) Ryanodol action on calcium sparks in ventricular myocytes. PflüGers Archiv : European Journal of Physiology. 460: 767-76
Johnson SR, Copello JA, Evans MS, et al. (2010) A biochemical characterization of the major peptides from the Venom of the giant Neotropical hunting ant Dinoponera australis. Toxicon : Official Journal of the International Society On Toxinology. 55: 702-10
Diaz-Sylvester PL, Copello JA. (2009) Voltage-dependent modulation of cardiac ryanodine receptors (RyR2) by protamine. Plos One. 4: e8315
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