Hitesh K. Agarwal, Ph.D.

Affiliations: 
2008 University of Rhode Island, Providence, RI, United States 
Area:
Pharmaceutical Chemistry, Pharmacology
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"Hitesh Agarwal"
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Keykavous Parang grad student 2008 University of Rhode Island
 (Design and evaluation of nucleoside derivatives for targeted drug delivery and therapeutic applications.)
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Publications

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Agarwal HK, Chhikara BS, Doncel GF, et al. (2017) Synthesis and anti-HIV activities of unsymmetrical long chain dicarboxylate esters of dinucleoside reverse transcriptase inhibitors. Bioorganic & Medicinal Chemistry Letters
Agarwal HK, Khalil A, Ishita K, et al. (2015) Synthesis and evaluation of thymidine kinase 1-targeting carboranyl pyrimidine nucleoside analogs for boron neutron capture therapy of cancer. European Journal of Medicinal Chemistry. 100: 197-209
Pemmaraju BP, Malekar S, Agarwal HK, et al. (2015) Design, synthesis, antiviral activity, and pre-formulation development of poly-L-arginine-fatty acyl derivatives of nucleoside reverse transcriptase inhibitors. Nucleosides, Nucleotides & Nucleic Acids. 34: 1-15
Fowler BJ, Gelfand BD, Kim Y, et al. (2014) Nucleoside reverse transcriptase inhibitors possess intrinsic anti-inflammatory activity. Science (New York, N.Y.). 346: 1000-3
Fonville JM, Wilks SH, James SL, et al. (2014) Antibody landscapes after influenza virus infection or vaccination. Science (New York, N.Y.). 346: 996-1000
Pemmaraju B, Agarwal HK, Oh D, et al. (2014) Synthesis and Biological Evaluation of 5'-O-Dicarboxylic Fatty Acyl Monoester Derivatives of Anti-HIV Nucleoside Reverse Transcriptase Inhibitors. Tetrahedron Letters. 55: 1983-1986
Sjuvarsson E, Damaraju VL, Mowles D, et al. (2013) Cellular influx, efflux, and anabolism of 3-carboranyl thymidine analogs: potential boron delivery agents for neutron capture therapy. The Journal of Pharmacology and Experimental Therapeutics. 347: 388-97
Agarwal HK, McElroy CA, Sjuvarsson E, et al. (2013) Synthesis of N3-substituted carboranyl thymidine bioconjugates and their evaluation as substrates of recombinant human thymidine kinase 1. European Journal of Medicinal Chemistry. 60: 456-68
Endeshaw M, Zhu X, He S, et al. (2013) 8,8-dialkyldihydroberberines with potent antiprotozoal activity. Journal of Natural Products. 76: 311-5
Agarwal HK, Chhikara BS, Bhavaraju S, et al. (2013) Emtricitabine prodrugs with improved anti-HIV activity and cellular uptake. Molecular Pharmaceutics. 10: 467-76
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