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Bryan T. Greene, Ph.D.

Affiliations: 
2003 Wake Forest University School of Medicine, Winston-Salem, NC, United States 
Area:
Oncology
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Suzy V. Torti grad student 2003 Wake Forest School of Medicine
 (Mechanistic studies of tachpyridine, a novel iron chelator and potential anti-cancer agent.)

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Publications

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Hughes AD, Marshall JR, Keller E, et al. (2014) Differential drug responses of circulating tumor cells within patient blood. Cancer Letters. 352: 28-35
Greene BT, Hughes AD, King MR. (2012) Circulating tumor cells: the substrate of personalized medicine? Frontiers in Oncology. 2: 69
Hughes AD, Mattison J, Powderly JD, et al. (2012) Rapid isolation of viable circulating tumor cells from patient blood samples. Journal of Visualized Experiments : Jove. e4248
Hughes AD, Mattison J, Western LT, et al. (2012) Microtube device for selectin-mediated capture of viable circulating tumor cells from blood. Clinical Chemistry. 58: 846-53
Alexander RL, Greene BT, Torti SV, et al. (2005) A novel phospholipid gemcitabine conjugate is able to bypass three drug-resistance mechanisms. Cancer Chemotherapy and Pharmacology. 56: 15-21
Buss JL, Greene BT, Turner J, et al. (2004) Iron chelators in cancer chemotherapy. Current Topics in Medicinal Chemistry. 4: 1623-35
Zhao R, Planalp RP, Ma R, et al. (2004) Role of zinc and iron chelation in apoptosis mediated by tachpyridine, an anti-cancer iron chelator. Biochemical Pharmacology. 67: 1677-88
Greene BT, Thorburn J, Willingham MC, et al. (2002) Activation of caspase pathways during iron chelator-mediated apoptosis. The Journal of Biological Chemistry. 277: 25568-75
Abeysinghe RD, Greene BT, Haynes R, et al. (2001) p53-independent apoptosis mediated by tachpyridine, an anti-cancer iron chelator. Carcinogenesis. 22: 1607-14
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