Steven J. Berthel
Affiliations: | Hoffmann-La Roche |
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Parents
Sign in to add mentor| Gordon W. Gribble | grad student | 1984-1990 | Dartmouth |
| Leon Ghosez | post-doc | 1990-1991 | Université Catholique de Louvain (Belgium) |
| Gary L Olson | post-doc | 1991-1992 | Hoffmann-La Roche |
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Publications
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| Qian Y, Corbett WL, Berthel SJ, et al. (2013) Identification of RO4597014, a Glucokinase Activator Studied in the Clinic for the Treatment of Type 2 Diabetes. Acs Medicinal Chemistry Letters. 4: 414-8 |
| Cheung AW, Banner B, Bose J, et al. (2012) 7-Phenyl-pyrido[2,3-d]pyrimidine-2,4-diamines: novel and highly selective protein tyrosine phosphatase 1B inhibitors. Bioorganic & Medicinal Chemistry Letters. 22: 7518-22 |
| GRIBBLE GW, BERTHEL SJ. (2010) ChemInform Abstract: Synthetic Approaches to Indolo(2,3-a)carbazole Alkaloids. Syntheses of Arcyriaflavin A (IVb) and AT2433-B Aglycone Cheminform. 24: no-no |
| Tilley J, Grimsby J, Erickson S, et al. (2010) Diabetes Drugs: Present and Emerging Burger's Medicinal Chemistry and Drug Discovery. 1-38 |
| Grimsby J, Berthel SJ, Sarabu R. (2008) Glucokinase activators for the potential treatment of type 2 diabetes Current Topics in Medicinal Chemistry. 8: 1524-1532 |
| Sarabu R, Berthel SJ, Kester RF, et al. (2008) Glucokinase activators as new type 2 diabetes therapeutic agents Expert Opinion On Therapeutic Patents. 18: 759-768 |
| Berthel SJ, Marks IM, Yin X, et al. (2002) Identification of phenyl-pyridine-2-carboxylic acid derivatives as novel cell cycle inhibitors with increased selectivity for cancer cells. Anti-Cancer Drugs. 13: 359-66 |
| Bolin DR, Swain AL, Sarabu R, et al. (2000) Peptide and peptide mimetic inhibitors of antigen presentation by HLA-DR class II MHC molecules. Design, structure-activity relationships, and X-ray crystal structures. Journal of Medicinal Chemistry. 43: 2135-48 |
| Falcioni F, Ito K, Vidovic D, et al. (1999) Peptidomimetic compounds that inhibit antigen presentation by autoimmune disease-associated class II major histocompatibility molecules. Nature Biotechnology. 17: 562-7 |
| Gribble GW, Berthel SJ. (1993) A Survey of Indolo [2,3-a] carbazole Alkaloids and Related Natural Products Studies in Natural Products Chemistry. 12: 365-409 |