Leon Ghosez, Ph.D.

Organic & Medicinal Chemistry Institut Européen de Chimie et Biologie 
total synthesis, synthetic methods, electrophilic catalysis, serine proteases, medicinal chemistry
"Leon Ghosez"

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Ramirez M, Li W, Lam YH, et al. (2020) Mechanisms and Conformational Control of (4+2) and (2+2) Cycloadditions of Dienes to Keteniminium Cations. The Journal of Organic Chemistry
Munyemana F, George I, Devos A, et al. (2016) A mild method for the replacement of a hydroxyl group by halogen. 1. Scope and chemoselectivity Tetrahedron. 72: 420-430
Mendoza O, Rossey G, Ghosez L. (2011) Brönsted acid-catalyzed synthesis of diarylmethanes under non-genotoxic conditions Tetrahedron Letters. 52: 2235-2239
Commandeur C, Commandeur M, Bathany K, et al. (2011) Study of the oxidation of 3-hydroxypyrroloindoles to pyrrolobenzoxazine alkaloids Tetrahedron. 67: 9899-9908
Mendoza O, Rossey G, Ghosez L. (2010) Trialkylsilyl triflimides as easily tunable organocatalysts for allylation and benzylation of silyl carbon nucleophiles with non-genotoxic reagents Tetrahedron Letters. 51: 2571-2575
Marchand-Brynaert J, Ferroud D, Serckx-Poncin B, et al. (2010) Synthesis and Stability of Functionalized Epoxides Topologically Related To Beta-lactam Antibiotics Bulletin Des SociéTéS Chimiques Belges. 99: 1075-1084
Zhu W, Mena M, Jnoff E, et al. (2009) Multicomponent reactions for the synthesis of complex piperidine scaffolds. Angewandte Chemie (International Ed. in English). 48: 5880-3
Commandeur M, Commandeur C, Paolis MD, et al. (2009) Studies related to the total synthesis of the sesquiterpene core of the pyrrolobenzoxazine natural products CJ-12662 and CJ-12663 Tetrahedron Letters. 50: 3359-3362
Yang G, Ghosez L. (2009) Synthesis of enantiopure α-chlorocyclobutanones and cyclobutanols as scaffolds for the diverted synthesis of serine protease inhibitors European Journal of Organic Chemistry. 1738-1748
Ghosez L, Bonifazi D. (2009) Ahead of and behind the show: A special issue dedicated to porfessor Alain Krief European Journal of Organic Chemistry. 1640
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