Plamen P. Christov, Ph.D.

2007 Vanderbilt University, Nashville, TN 
Organic Chemistry
"Plamen Christov"
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Carmelo Rizzo grad student 2007 Vanderbilt
 (Synthesis and in vitro replication studies of N5-alkylated formamidopyrimidine (FAPy-dGuo) adducts in DNA.)
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Fu Y, Christov PP, Kingsley PJ, et al. (2023) Base-Displaced Intercalated Structure of the 3-(2-Deoxy-β-D-erythropentofuranosyl)-pyrimido[1,2-]purine-6,10(3,5)-dione (6-oxo-MdG) Lesion in DNA. Chemical Research in Toxicology
Christov PP, Richie-Jannetta R, Kingsley PJ, et al. (2021) Site-Specific Synthesis of Oligonucleotides Containing 6-Oxo-MdG, the Genomic Metabolite of MdG, and Liquid Chromatography-Tandem Mass Spectrometry Analysis of Its In Vitro Bypass by Human Polymerase ι. Chemical Research in Toxicology
Bradley NP, Washburn LA, Christov PP, et al. (2020) Escherichia coli YcaQ is a DNA glycosylase that unhooks DNA interstrand crosslinks. Nucleic Acids Research
Minko IG, Christov PP, Li L, et al. (2018) Processing of N-substituted formamidopyrimidine DNA adducts by DNA glycosylases NEIL1 and NEIL3. Dna Repair
Lepesheva G, Christov P, Sulikowski GA, et al. (2017) A convergent, scalable and stereoselective synthesis of azole CYP51 inhibitors. Tetrahedron Letters. 58: 4248-4250
Gruppi F, Hejazi L, Christov PP, et al. (2015) Characterization of nitrogen mustard formamidopyrimidine adduct formation of bis(2-chloroethyl)ethylamine with calf thymus DNA and a human mammary cancer cell line. Chemical Research in Toxicology. 28: 1850-60
Patra A, Banerjee S, Johnson Salyard TL, et al. (2015) Structural Basis for Error-Free Bypass of the 5-N-Methylformamidopyrimidine-dG Lesion by Human DNA Polymerase η and Sulfolobus solfataricus P2 Polymerase IV. Journal of the American Chemical Society. 137: 7011-4
Chang SC, Fedeles BI, Wu J, et al. (2015) Next-generation sequencing reveals the biological significance of the N2,3-ethenoguanine lesion in vivo. Nucleic Acids Research. 43: 5489-500
Christov PP, Son KJ, Rizzo CJ. (2014) Synthesis and characterization of oligonucleotides containing a nitrogen mustard formamidopyrimidine monoadduct of deoxyguanosine. Chemical Research in Toxicology. 27: 1610-8
Fu Y, Nath RG, Dyba M, et al. (2014) In vivo detection of a novel endogenous etheno-DNA adduct derived from arachidonic acid and the effects of antioxidants on its formation. Free Radical Biology & Medicine. 73: 12-20
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