Anna K. H. Hirsch
Affiliations: | University of Groningen, Groningen, Netherlands |
Area:
drug designWebsite:
http://www.rug.nl/scheikunde/onderzoek/scholen/stratingh/groepen/hirsch/object521614416?lang=nlGoogle:
"Anna Hirsch"Bio:
http://dx.doi.org/10.3929/ethz-a-005664687
Mean distance: 7.51 | S | N | B | C | P |
Parents
Sign in to add mentorTimothy F. Jamison | research assistant | MIT | ||
Steven Victor Ley | research assistant | Cambridge | ||
François N. Diederich | grad student | 2008 | ETH Zürich | |
(A Novel Approach towards Antimalarials: Design and Synthesis of Inhibitors of the Kinase IspE) | ||||
Jean-Marie Lehn | post-doc | 2010 | Université Louis Pasteur, Strasbourg |
Collaborators
Sign in to add collaboratorPhilipp Klahn | collaborator | 2019- | Helmholtz Centre for Infection Research/Universitaet des Saarlandes |
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Publications
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Gierse RM, Redeem E, Diamanti E, et al. (2017) DXS as a target for structure-based drug design. Future Medicinal Chemistry. 9: 1277-1294 |
Scheepstra M, Andrei SA, Unver MY, et al. (2017) Designed Spiroketal Protein Modulation. Angewandte Chemie (International Ed. in English) |
Liu Y, Lehn JM, Hirsch AK. (2017) Molecular Biodynamers: Dynamic Covalent Analogues of Biopolymers. Accounts of Chemical Research |
Dockerty P, Edens JG, Tol MB, et al. (2017) Bicyclic enol cyclocarbamates inhibit penicillin-binding proteins. Organic & Biomolecular Chemistry |
Wieczorek S, Remmler D, Masini T, et al. (2016) Equipping nanocarriers specifically toward cargo: A competitive study on solubilizing related photosensitizers for photodynamic therapy. Bioconjugate Chemistry |
Mondal M, Unver MY, Pal A, et al. (2016) Fragment-Based Drug Design Facilitated by Protein-Templated Click Chemistry: Fragment Linking and -Optimization of Inhibitors of the Aspartic Protease Endothiapepsin. Chemistry (Weinheim An Der Bergstrasse, Germany) |
Masini T, Birkaya B, van Dijk S, et al. (2016) Furoates and thenoates inhibit pyruvate dehydrogenase kinase 2 allosterically by binding to its pyruvate regulatory site. Journal of Enzyme Inhibition and Medicinal Chemistry. 1-6 |
Mondal M, Radeva N, Fanlo-Virgós H, et al. (2016) Fragment Linking and Optimization of Inhibitors of the Aspartic Protease Endothiapepsin: Fragment-Based Drug Design Facilitated by Dynamic Combinatorial Chemistry. Angewandte Chemie (International Ed. in English) |
Monjas L, Hirsch AK. (2015) Harnessing dynamic combinatorial chemistry in the search for new ligands for protein targets. Future Medicinal Chemistry |
Masini T, Lacy B, Monjas L, et al. (2015) Validation of a homology model of Mycobacterium tuberculosis DXS: rationalization of observed activities of thiamine derivatives as potent inhibitors of two orthologues of DXS. Organic & Biomolecular Chemistry |