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Anna K. H. Hirsch

University of Groningen, Groningen, Netherlands 
drug design
"Anna Hirsch"

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Timothy F. Jamison research assistant MIT
Steven Victor Ley research assistant Cambridge
François N. Diederich grad student 2008 ETH Zürich
 (A Novel Approach towards Antimalarials: Design and Synthesis of Inhibitors of the Kinase IspE)
Jean-Marie Lehn post-doc 2010 Université Louis Pasteur, Strasbourg
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Gierse RM, Redeem E, Diamanti E, et al. (2017) DXS as a target for structure-based drug design. Future Medicinal Chemistry. 9: 1277-1294
Scheepstra M, Andrei SA, Unver MY, et al. (2017) Designed Spiroketal Protein Modulation. Angewandte Chemie (International Ed. in English)
Liu Y, Lehn JM, Hirsch AK. (2017) Molecular Biodynamers: Dynamic Covalent Analogues of Biopolymers. Accounts of Chemical Research
Dockerty P, Edens JG, Tol MB, et al. (2017) Bicyclic enol cyclocarbamates inhibit penicillin-binding proteins. Organic & Biomolecular Chemistry
Wieczorek S, Remmler D, Masini T, et al. (2016) Equipping nanocarriers specifically toward cargo: A competitive study on solubilizing related photosensitizers for photodynamic therapy. Bioconjugate Chemistry
Mondal M, Unver MY, Pal A, et al. (2016) Fragment-Based Drug Design Facilitated by Protein-Templated Click Chemistry: Fragment Linking and -Optimization of Inhibitors of the Aspartic Protease Endothiapepsin. Chemistry (Weinheim An Der Bergstrasse, Germany)
Masini T, Birkaya B, van Dijk S, et al. (2016) Furoates and thenoates inhibit pyruvate dehydrogenase kinase 2 allosterically by binding to its pyruvate regulatory site. Journal of Enzyme Inhibition and Medicinal Chemistry. 1-6
Mondal M, Radeva N, Fanlo-Virgós H, et al. (2016) Fragment Linking and Optimization of Inhibitors of the Aspartic Protease Endothiapepsin: Fragment-Based Drug Design Facilitated by Dynamic Combinatorial Chemistry. Angewandte Chemie (International Ed. in English)
Monjas L, Hirsch AK. (2015) Harnessing dynamic combinatorial chemistry in the search for new ligands for protein targets. Future Medicinal Chemistry
Masini T, Lacy B, Monjas L, et al. (2015) Validation of a homology model of Mycobacterium tuberculosis DXS: rationalization of observed activities of thiamine derivatives as potent inhibitors of two orthologues of DXS. Organic & Biomolecular Chemistry
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