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Emad Saleem Alnemri

Genetics Thomas Jefferson University 
Cell Biology, Biochemistry, Immunology
"Emad Saleem Alnemri"

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Gerald Litwack grad student 1991 Temple University
 (Molecular mechanisms of glucocorticoid-induced programmed cell death in lymphoid tissues.)
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Mandal P, Nagrani LN, Hernandez L, et al. (2021) Multiple Autonomous Cell Death Suppression Strategies Ensure Cytomegalovirus Fitness. Viruses. 13
Ariana A, Alturki NA, Hajjar S, et al. (2020) Tristetraprolin regulates necroptosis during tonic Toll-like receptor 4 (TLR4) signaling in murine macrophages. The Journal of Biological Chemistry
Rogers C, Alnemri ES. (2019) Gasdermins in Apoptosis: New players in an Old Game. The Yale Journal of Biology and Medicine. 92: 603-617
Erkes DA, Cai W, Sanchez IM, et al. (2019) Mutant BRAF and MEK inhibitors regulate the tumor immune microenvironment via pyroptosis. Cancer Discovery
Rogers C, Alnemri ES. (2019) Gasdermins: novel mitochondrial pore-forming proteins. Molecular & Cellular Oncology. 6: e1621501
Rogers C, Erkes DA, Nardone A, et al. (2019) Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation. Nature Communications. 10: 1689
Hara H, Seregin SS, Yang D, et al. (2018) The NLRP6 Inflammasome Recognizes Lipoteichoic Acid and Regulates Gram-Positive Pathogen Infection. Cell
Barry R, John SW, Liccardi G, et al. (2018) SUMO-mediated regulation of NLRP3 modulates inflammasome activity. Nature Communications. 9: 3001
Rodrigue-Gervais IG, Doiron K, Champagne C, et al. (2018) The mitochondrial protease HtrA2 restricts the NLRP3 and AIM2 inflammasomes. Scientific Reports. 8: 8446
Alturki NA, McComb S, Ariana A, et al. (2018) Triad3a induces the degradation of early necrosome to limit RipK1-dependent cytokine production and necroptosis. Cell Death & Disease. 9: 592
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