Simon H. Friedman, Ph.D.

Affiliations: 
Pharmaceutical Sciences University of Missouri Kansas City 
Area:
Bioorganic Chemistry/Chemical Biology
Website:
http://friedmanlaboratory.org/
Google:
"Friedman laboratory"
Bio:

Prof. Simon H. Friedman was born and raised in Chicago, where he attended public schools. He then entered MIT, and received an SB in Chemistry in 1989. During this time he did 3 years of undergraduate research in the lab of Prof. George Benedek, under the guidance of Dr. John Thomson. His work focussed on the development of anti-cataract compounds, and resulted in him being named as co-inventor on multiple US and international patents for these discoveries.
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Publications

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Ansong M, Kover K, Shah P, et al. (2024) A Green Light-Activated Insulin Depot with Ultrafast In Vivo Efficiency in the Subcutaneous Space. Acs Biomaterials Science & Engineering
Nadendla K, Chintala S, Kover K, et al. (2023) In vivo variable and multi-day response from an insulin-releasing photoactivated depot. Bioorganic & Medicinal Chemistry Letters. 92: 129388
Friedman SH. (2019) Replacing Pumps with Light Controlled Insulin Delivery. Current Diabetes Reports. 19: 122
Sarode BR, Kover K, Friedman SH. (2019) Visible-Light-Activated High-Density Materials for Controlled in Vivo Insulin Release. Molecular Pharmaceutics
Nadendla K, Sarode B, Friedman SH. (2019) Chemical modification of proteins with photocleavable groups. Methods in Enzymology. 624: 113-128
Nadendla K, Sarode BR, Friedman SH. (2019) Hydrophobic Tags for Highly Efficient Light Activated Protein Release. Molecular Pharmaceutics
Jain N, Friedman SH. (2018) Multiple weak intercalation as a strategy for the inhibition of polymerases. Bioorganic & Medicinal Chemistry Letters
Jain N, Friedman SH. (2018) A Tetra-Orthogonal Strategy for the Efficient Synthesis of Scaffolds Based on Cyclic Peptides. International Journal of Peptide Research and Therapeutics. 24: 535-542
Jain PK, Friedman SH. (2018) The ULTIMATE Reagent: A Universal Photo-Cleavable & Clickable Reagent for the Regiospecific and Reversible End Labeling of Any Nucleic Acid. Chembiochem : a European Journal of Chemical Biology
Jain PK, Friedman SH. (2018) Front Cover: The ULTIMATE Reagent: A Universal Photocleavable and Clickable Reagent for the Regiospecific and Reversible End Labeling of Any Nucleic Acid (ChemBioChem 12/2018) Chembiochem. 19: 1196-1196
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