George L. Kenyon

Affiliations: 
1998-2010 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Pharmaceutical Chemistry
Website:
http://faculty-history.dc.umich.edu/faculty/george-l-kenyon
Google:
"George Kenyon"
Bio:

http://chemistry.library.nd.edu/resources/genealogy/chemistry/documents/KenyonGL.pdf

Mean distance: 7.25
 
SNBCP
Cross-listing: MichiganTree

Parents

Sign in to add mentor
Frank H. Westheimer grad student 1965 Harvard
 (Studies on the mechanism of the alkaline decomposition of beta-haloalkylphosphonic acids)

Children

Sign in to add trainee
JoAnne Stubbe grad student 1971 UC Berkeley
Michael A. Marletta grad student 1978 UCSF
Patricia C. Babbitt grad student 1988 UCSF
Simon H. Friedman grad student 1989-1996 UCSF
Sean M. Kerwin post-doc 1989-1991 UCSF
Jawad Alzeer post-doc 1998-2000 Michigan - Ann Arbor
Michael J. McLeish research scientist 1996-1997 UCSF
BETA: Related publications

Publications

You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect.

Brandt GS, Kneen MM, Chakraborty S, et al. (2009) Snapshot of a reaction intermediate: analysis of benzoylformate decarboxylase in complex with a benzoylphosphonate inhibitor. Biochemistry. 48: 3247-57
Chakraborty S, Nemeria NS, Balakrishnan A, et al. (2009) Detection and time course of formation of major thiamin diphosphate-bound covalent intermediates derived from a chromophoric substrate analogue on benzoylformate decarboxylase. Biochemistry. 48: 981-94
Wang PF, Yep A, Kenyon GL, et al. (2009) Using directed evolution to probe the substrate specificity of mandelamide hydrolase. Protein Engineering, Design & Selection : Peds. 22: 103-10
Brandt GS, Nemeria N, Chakraborty S, et al. (2008) Probing the active center of benzaldehyde lyase with substitutions and the pseudosubstrate analogue benzoylphosphonic acid methyl ester. Biochemistry. 47: 7734-43
Yeung CK, Yep A, Kenyon GL, et al. (2008) Physical, kinetic and spectrophotometric studies of a NAD(P)-dependent benzaldehyde dehydrogenase from Pseudomonas putida ATCC 12633. Biochimica Et Biophysica Acta. 1784: 1248-55
Yep A, Kenyon GL, McLeish MJ. (2008) Saturation mutagenesis of putative catalytic residues of benzoylformate decarboxylase provides a challenge to the accepted mechanism. Proceedings of the National Academy of Sciences of the United States of America. 105: 5733-8
Chakraborty S, Nemeria N, Yep A, et al. (2008) Mechanism of benzaldehyde lyase studied via thiamin diphosphate-bound intermediates and kinetic isotope effects. Biochemistry. 47: 3800-9
Nemeria N, Korotchkina L, McLeish MJ, et al. (2007) Elucidation of the chemistry of enzyme-bound thiamin diphosphate prior to substrate binding: defining internal equilibria among tautomeric and ionization states. Biochemistry. 46: 10739-44
Bera AK, Polovnikova LS, Roestamadji J, et al. (2007) Mechanism-based inactivation of benzoylformate decarboxylase, a thiamin diphosphate-dependent enzyme. Journal of the American Chemical Society. 129: 4120-1
Yep A, Kenyon GL, McLeish MJ. (2006) Determinants of substrate specificity in KdcA, a thiamin diphosphate-dependent decarboxylase. Bioorganic Chemistry. 34: 325-36
See more...