Beshay N. Zordoky, Ph.D.

Affiliations: 
2012 University of Alberta, Edmonton, Alberta, Canada 
Area:
Pharmaceutical Chemistry, Physiology Biology
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Ayman El-Kadi grad student 2012 University of Alberta
 (Role of cytochrome P450 enzymes in the pathogenesis of cardiac hypertrophy and doxorubicin-induced cardiotoxicity.)
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Publications

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Dabour MS, Abdelgawad IY, Sadaf B, et al. (2024) Losmapimod ameliorates doxorubicin-induced cardiotoxicity through attenuating senescence and inflammatory pathways. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 179: 117288
Liu J, Curtin C, Lall R, et al. (2024) Inhibition of Cyp1a Protects Mice against Anthracycline Cardiomyopathy. Biorxiv : the Preprint Server For Biology
Abdelgawad IY, George B, Grant MKO, et al. (2024) Sex-related differences in delayed doxorubicin-induced cardiac dysfunction in C57BL/6 mice. Archives of Toxicology
Agostinucci K, Grant MKO, Seelig D, et al. (2022) Divergent Cardiac Effects of Angiotensin II and Isoproterenol Following Juvenile Exposure to Doxorubicin. Frontiers in Cardiovascular Medicine. 9: 742193
Grant MKO, Abdelgawad IY, Lewis CA, et al. (2020) Lack of sexual dimorphism in a mouse model of isoproterenol-induced cardiac dysfunction. Plos One. 15: e0232507
Grant MKO, Abdelgawad IY, Lewis CA, et al. (2020) Sexual Dimorphism in Doxorubicin-induced Systemic Inflammation: Implications for Hepatic Cytochrome P450 Regulation. International Journal of Molecular Sciences. 21
Grant MKO, Seelig DM, Sharkey LC, et al. (2019) Sexual dimorphism of acute doxorubicin-induced nephrotoxicity in C57Bl/6 mice. Plos One. 14: e0212486
Matsumura N, Zordoky BN, Robertson IM, et al. (2018) Co-administration of resveratrol with doxorubicin in young mice attenuates detrimental late-occurring cardiovascular changes. Cardiovascular Research
Grant MK, Seelig DM, Sharkey LC, et al. (2017) Sex-dependent alteration of cardiac cytochrome P450 gene expression by doxorubicin in C57Bl/6 mice. Biology of Sex Differences. 8: 1
Sung MM, Zordoky BN, Bujak AL, et al. (2015) AMPK deficiency in cardiac muscle results in dilated cardiomyopathy in the absence of changes in energy metabolism. Cardiovascular Research. 107: 235-45
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