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Sumith A. Kularatne

Affiliations: 
On Target Laboratory 
Area:
Oncology, Drug design and development, Targeted-drugs for cancer and inflammatory diseases, immunotherapy, Image-guided surgery,
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"Sumith Kularatne"
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Parents

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Philip S. Low grad student 2005-2009 Purdue
Peter G. Schultz post-doc 2009-2012 Scripps Institute

Children

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Joseph Didelot research assistant 2018- On Target Laboratory
Katelyn Kyung Huff research assistant 2018- On Target Laboratory
Valerie Paker research assistant 2013-2014 On Target Laboratory
Carrie H. Myers research assistant 2013-2016 On Target Laboratory
Dhwani Haria research assistant 2016-2017 On Target Laboratory
Patrick C Curley research assistant 2017-2018 On Target Laboratory
Pravin D. Gagare research scientist 2012- On Target Laboratory
Ananda K. Kanduluru research scientist 2016- On Target Laboratory
Mini Thomas research scientist 2016- On Target Laboratory
Micheal Alley research scientist 2018- On Target Laboratory
Mohammad Norshi research scientist 2012-2014 On Target Laboratory
Sherine Abdelmwla research scientist 2014-2014 On Target Laboratory
Sakkarapalayam M. Mahalingam research scientist 2012-2018 Purdue

Collaborators

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Philip S. Low collaborator 2012- Purdue
Walter Henne, Jr collaborator 2013- Governer Stae University
Gultiken Gulsen collaborator 2014- UC Irvine
Sunil Singhal collaborator 2014- University of Pennsylvania Medical School
Gert Breur collaborator 2015- Purdue
Umamaheswar Duvvuri collaborator 2016- University of Pittsburgh Medical Center
Indrapal Sakaria collaborator 2016- University of Pittsburgh Medical Center
Brandy Cichocki collaborator 2018- Purdue
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Publications

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Stibbe JA, de Barros HA, Linders DGJ, et al. (2023) First-in-patient study of OTL78 for intraoperative fluorescence imaging of prostate-specific membrane antigen-positive prostate cancer: a single-arm, phase 2a, feasibility trial. The Lancet. Oncology. 24: 457-467
Kennedy GT, Azari FS, Bernstein E, et al. (2022) Targeted detection of cancer at the cellular level during biopsy by near-infrared confocal laser endomicroscopy. Nature Communications. 13: 2711
Cresswell GM, Wang B, Kischuk EM, et al. (2020) Folate Receptor Beta Designates Immunosuppressive Tumor-Associated Myeloid Cells that Can Be Reprogrammed with Folate-Targeted Drugs. Cancer Research
Mahalingam SM, Kularatne SA, Myers CH, et al. (2018) Evaluation of Novel Tumor-Targeted Near-Infrared Probe for Fluorescence-Guided Surgery of Cancer. Journal of Medicinal Chemistry
Kularatne SA, Thomas M, Myers CH, et al. (2018) Evaluation of Novel Prostate-Specific Membrane Antigen-Targeted Near-Infrared Imaging Agent for Fluorescence-Guided Surgery for Prostate Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research
Marks IS, Gardeen SS, Kurdziel SJ, et al. (2018) Development of a Small Molecule Tubulysin B Conjugate for Treatment of Carbonic Anhydrase IX Receptor Expressing Cancers. Molecular Pharmaceutics
Predina JD, Newton AD, Xia L, et al. (2018) An open label trial of folate receptor-targeted intraoperative molecular imaging to localize pulmonary squamous cell carcinomas. Oncotarget. 9: 13517-13529
Predina JD, Newton AD, Connolly C, et al. (2017) Identification of a Folate Receptor-Targeted Near-Infrared Molecular Contrast Agent to Localize Pulmonary Adenocarcinomas. Molecular Therapy : the Journal of the American Society of Gene Therapy
Predina JD, Newton AD, Keating J, et al. (2017) Intraoperative Molecular Imaging Combined With Positron Emission Tomography Improves Surgical Management of Peripheral Malignant Pulmonary Nodules. Annals of Surgery
De Jesus E, Keating JJ, Kularatne SA, et al. (2015) Comparison of Folate Receptor Targeted Optical Contrast Agents for Intraoperative Molecular Imaging. International Journal of Molecular Imaging. 2015: 469047
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