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Giovanni Piersanti, Ph.D.

Affiliations: 
Biomolecular Sciences University of Urbino 
Area:
Organic Chemistry, Medicinal Chemistry
Website:
http://www.uniurb.it/MedChem/PiersantiResearch/
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"Giovanni Piersanti"
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Publications

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Varone E, Retini M, Cherubini A, et al. (2025) Small molecule-mediated inhibition of the oxidoreductase ERO1A restrains aggressive breast cancer by impairing VEGF and PD-L1 in the tumor microenvironment. Cell Death & Disease. 16: 105
van der Heide P, Retini M, Fanini F, et al. (2024) Giese-type alkylation of dehydroalanine derivatives via silane-mediated alkyl bromide activation. Beilstein Journal of Organic Chemistry. 20: 3274-3280
Pecchini P, Fochi M, Bartoccini F, et al. (2024) Enantioselective organocatalytic strategies to access noncanonical α-amino acids. Chemical Science. 15: 5832-5868
Regni A, Bartoccini F, Piersanti G. (2023) Photoredox catalysis enabling decarboxylative radical cyclization of γ,γ-dimethylallyltryptophan (DMAT) derivatives: formal synthesis of 6,7-secoagroclavine. Beilstein Journal of Organic Chemistry. 19: 918-927
Retini M, Bartolucci S, Bartoccini F, et al. (2022) Asymmetric Alkylation of Cyclic Ketones with Dehydroalanine via H-Bond-Directing Enamine Catalysis: Straightforward Access to Enantiopure Unnatural α-Amino Acids. Chemistry (Weinheim An Der Bergstrasse, Germany). e202201994
Bartoccini F, Regni A, Retini M, et al. (2021) Concise catalytic asymmetric synthesis of (R)-4-amino Uhle's ketone. Organic & Biomolecular Chemistry. 19: 2932-2940
Linciano P, Cullia G, Borsari C, et al. (2020) Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign. European Journal of Medicinal Chemistry. 189: 112047
Bartoccini F, Fanini F, Retini M, et al. (2020) General synthesis of unnatural 4-, 5-, 6-, and 7-bromo-d-tryptophans by means of a regioselective indole alkylation Tetrahedron Letters. 61: 151923
Bartoccini F, Mari M, Retini M, et al. (2020) Single‐Step Synthesis of Dehydroalanine Derivatives via a Brønsted Acid‐Catalyzed Multicomponent Reaction Chemistryselect. 5: 3330-3336
Retini M, Bartolucci S, Bartoccini F, et al. (2019) Concise and Convergent Enantioselective Total Syntheses of (+)- and (-)-Fumimycin. The Journal of Organic Chemistry
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