Yuri Bolshan
Affiliations: | 2003-2008 | University of Toronto, Toronto, ON, Canada |
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Publications
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| Getlik M, Smil D, Zepeda-Velázquez C, et al. (2016) Structure-Based Optimization of a Small Molecule Antagonist of the Interaction Between WD Repeat-Containing Protein 5 (WDR5) and Mixed-Lineage Leukemia 1 (MLL1). Journal of Medicinal Chemistry |
| Taylor CL, Bolshan Y. (2015) Metal-free synthesis of ynones from acyl chlorides and potassium alkynyltrifluoroborate salts. Journal of Visualized Experiments : Jove |
| Taylor C, Bolshan Y. (2015) Metal-free methodology for the preparation of sterically hindered alkynoylphenols and its application to the synthesis of flavones and aurones Tetrahedron Letters. 56: 4392-4396 |
| Al-Awar R, Al-Awar R, Getlik M, et al. (2014) 287 The discovery and optimization of small molecule antagonists of the WDR5–MLL interaction European Journal of Cancer. 50: 95 |
| Bolshan Y, Getlik M, Kuznetsova E, et al. (2013) Synthesis, Optimization, and Evaluation of Novel Small Molecules as Antagonists of WDR5-MLL Interaction. Acs Medicinal Chemistry Letters. 4: 353-7 |
| Li B, Tempel W, Smil D, et al. (2013) Crystal structures of Klebsiella pneumoniae pantothenate kinase in complex with N-substituted pantothenamides. Proteins. 81: 1466-72 |
| Yu W, Smil D, Li F, et al. (2013) Bromo-deaza-SAH: a potent and selective DOT1L inhibitor. Bioorganic & Medicinal Chemistry. 21: 1787-94 |
| Bullwinkle TJ, Zou SB, Rajkovic A, et al. (2013) (R)-β-lysine-modified elongation factor P functions in translation elongation. The Journal of Biological Chemistry. 288: 4416-23 |
| Senisterra G, Wu H, Allali-Hassani A, et al. (2013) Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5. The Biochemical Journal. 449: 151-9 |
| Siarheyeva A, Senisterra G, Allali-Hassani A, et al. (2012) An allosteric inhibitor of protein arginine methyltransferase 3. Structure (London, England : 1993). 20: 1425-35 |