Eric A. Wold

Affiliations: 
University of Texas Medical Branch, Galveston, TX 
Area:
Medicinal Chemistry, 5-HT2C Receptor, CNS Drug Discovery
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"Eric A. Wold UTMB"
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Jia Zhou grad student 2015- UTMB
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Publications

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Chen J, Garcia EJ, Merritt CR, et al. (2023) Discovery of Novel Oleamide Analogues as Brain-Penetrant Positive Allosteric Serotonin 5-HT Receptor and Dual 5-HT/5-HT Receptor Modulators. Journal of Medicinal Chemistry
Liu Z, Li Y, Chen H, et al. (2022) Discovery, X-ray Crystallography, and Anti-inflammatory Activity of Bromodomain-containing Protein 4 (BRD4) BD1 Inhibitors Targeting a Distinct New Binding Site. Journal of Medicinal Chemistry
Liu Z, Wang P, Wold EA, et al. (2021) Small-Molecule Inhibitors Targeting the Canonical WNT Signaling Pathway for the Treatment of Cancer. Journal of Medicinal Chemistry
Xu J, Berastegui-Cabrera J, Carretero-Ledesma M, et al. (2021) Discovery of a Small Molecule Inhibitor of Human Adenovirus Capable of Preventing Escape from the Endosome. International Journal of Molecular Sciences. 22
Ye N, Qin W, Tian S, et al. (2020) Small Molecules Selectively Targeting Sigma-1 Receptor for the Treatment of Neurological Diseases. Journal of Medicinal Chemistry
Wold EA, Garcia EJ, Wild C, et al. (2020) Discovery of 4-Phenylpiperidine-2-Carboxamide Analogues as Serotonin 5-HT2C Receptor Positive Allosteric Modulators with Enhanced Drug-Like Properties. Journal of Medicinal Chemistry
Liu Z, Chen H, Wang P, et al. (2020) Discovery of Orally Bioavailable Chromone Derivatives as Potent and Selective BRD4 Inhibitors: Scaffolding Hopping, Optimization and Pharmacological Evaluation. Journal of Medicinal Chemistry
Wold EA, Wild CT, Cunningham KA, et al. (2019) Targeting the 5-HT2C Receptor in Biological Context and the Current State of 5-HT2C Receptor Ligand Development. Current Topics in Medicinal Chemistry
Liu G, Yin T, Kim H, et al. (2019) Structure-activity relationship studies on Bax activator SMBA1 for the treatment of ER-positive and triple-negative breast cancer. European Journal of Medicinal Chemistry. 178: 589-605
Liu G, Wold EA, Zhou J. (2019) Applications of Bioorthogonal Chemistry in Tumor-Targeted Drug Discovery. Current Topics in Medicinal Chemistry
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