John W. Sedat

Biochemistry & Biophysics University of California, San Francisco, San Francisco, CA 
Nuclear Architecture and Chromosome Organization
"John W. Sedat"

John Sedat is Professor Emeritus in Biochemistry and Biophysics at the University of California, San Francisco. He received his Ph.D. in Biology from Caltech in Pasadena, CA in 1970 followed by postdoctoral study under Fred Sanger at the MRC in Cambridge, England. Subsequently, he spent approximately a year at the Hebrew University at Hadassah in Jerusalem, Israel where the Drosophila and chromosome study started. Several years at Yale followed, and he has been at UCSF since 1977.

Mean distance: 8.22


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Robert L. Sinsheimer grad student 1970 Caltech
 (On Bacterial and φX174 Messenger RNA Messenger RNA)
Frederick Sanger post-doc MRC-LMB


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Orion D. Weiner grad student (Neurotree)
Mark W. Hochstrasser grad student 1987 UCSF
Wallace F. Marshall grad student 1991-1997 UCSF
Aaron F. Straight grad student 1998 UCSF
Brian P. Harmon grad student 2002 UCSF
Bridget M. Hanser grad student 2003 UCSF
Michael G. Lowenstein grad student 2004 UCSF
Lin Shao grad student 2005 UCSF
Erik F. Hom grad student 2006 UCSF
Andrew Belmont post-doc UCSF (Cell Biology Tree)
Mats Gustafsson post-doc
Peter A. Kner post-doc 2004- University of Georgia
David A. Agard post-doc 1980 UCSF
Hank W. Bass post-doc 1992-1997 UCSF (Cell Biology Tree)
Peter M. Carlton research scientist (Cell Biology Tree)
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Croxford M, Elbaum M, Arigovindan M, et al. (2021) Entropy-regularized deconvolution of cellular cryotransmission electron tomograms. Proceedings of the National Academy of Sciences of the United States of America. 118
Waugh B, Wolf SG, Fass D, et al. (2020) Three-dimensional deconvolution processing for STEM cryotomography. Proceedings of the National Academy of Sciences of the United States of America
Arigovindan M, Fung JC, Elnatan D, et al. (2013) High-resolution restoration of 3D structures from widefield images with extreme low signal-to-noise-ratio. Proceedings of the National Academy of Sciences of the United States of America. 110: 17344-9
Nora EP, Lajoie BR, Schulz EG, et al. (2012) Spatial partitioning of the regulatory landscape of the X-inactivation centre Nature. 485: 381-385
Shao L, Winoto L, Agard DA, et al. (2012) Interferometer-based structured-illumination microscopy utilizing complementary phase relationship through constructive and destructive image detection by two cameras. Journal of Microscopy. 246: 229-36
Arigovindan M, Sedat JW, Agard DA. (2012) Effect of depth dependent spherical aberrations in 3D structured illumination microscopy. Optics Express. 20: 6527-41
Dobbie IM, King E, Parton RM, et al. (2011) OMX: a new platform for multimodal, multichannel wide-field imaging. Cold Spring Harbor Protocols. 2011: 899-909
Zheng SQ, Branlund E, Kesthelyi B, et al. (2011) A distributed multi-GPU system for high speed electron microscopic tomographic reconstruction. Ultramicroscopy. 111: 1137-43
Strukov YG, Sural TH, Kuroda MI, et al. (2011) Evidence of activity-specific, radial organization of mitotic chromosomes in Drosophila. Plos Biology. 9: e1000574
Kner P, Kam Z, Agard D, et al. (2011) Adaptive optics in wide-field microscopy Proceedings of Spie - the International Society For Optical Engineering. 7931
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