John R. Falck

University of Texas Southwestern Medical Center, Dallas, TX, United States 
Biochemistry, Medicinal chemistry, Organometallics, Natural products chemistry
"John R. Falck"

(born 1948)

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Gawrys O, Husková Z, Baranowska I, et al. (2020) Combined treatment with epoxyeicosatrienoic acid analog and 20-hydroxyeicosatetraenoic acid antagonist provides substantial hypotensive effect in spontaneously hypertensive rats. Journal of Hypertension
Guo Z, Lei J, Wu S, et al. (2020) Abstract 4372: Metformin inhibits nuclear localization of estrogen receptor alpha in breast cancer cells, in part, by inhibition of CYP-mediated epoxyeicosatrienoic acid (EET) biosynthesis Epidemiology. 80: 4372-4372
Walkowska A, Sadowski J, Cervenka L, et al. (2020) Acute hypotensive effect of EET‐A, a stable analog of epoxyeicosatrienic acid (EET), in spontaneously hypertensive rats: dependence on endogenous EETs activity The Faseb Journal. 34: 1-1
Gawrys O, Walkowska A, Kompanowska-Jezierska E, et al. (2020) Effective Antihypertensive Treatment with Epoxyeicosatrienoic Acid Analog (EET‐A) and 20‐HETE Antagonist (AAA) of Spontaneously Hypertensive Rats (SHR) The Faseb Journal. 34: 1-1
Adebesin AM, Wesser T, Vijaykumar J, et al. (2019) Development of Robust 17(R),18(S)-Epoxyeicosatetraenoic Acid (17,18-EEQ) Analogs as Potential Clinical Antiarrhythmic Agents. Journal of Medicinal Chemistry
Dakarapu R, Errabelli R, Manthati VL, et al. (2019) 19-Hydroxyeicosatetraenoic acid analogs: Antagonism of 20-hydroxyeicosatetraenoic acid-induced vascular sensitization and hypertension. Bioorganic & Medicinal Chemistry Letters. 126616
Hoff U, Bubalo G, Fechner M, et al. (2019) A synthetic epoxyeicosatrienoic acid analog prevents the initiation of ischemic acute kidney injury. Acta Physiologica (Oxford, England). e13297
Chen L, Tang S, Zhang FF, et al. (2019) CYP4A/20-HETE Regulates Ischemia-induced Neovascularization via Its Actions on Endothelial Progenitor and Preexisting Endothelial Cells. American Journal of Physiology. Heart and Circulatory Physiology
Song CY, Shin JS, Lew J, et al. (2019) Abstract P2029: Cytochrome P450 (CYP) 1B1-Estradiol Metabolite 2-Methoxyestradiol Protects Against Angiotensin II-induced Hypertension By Inhibiting CYP4A1 Expression 20-Hydroxyeicosatetraenoic Acid (20-HETE) Production In The Female Mice Hypertension. 74
Capdevila JH, Falck JR. (2018) The Arachidonic Acid Monooxygenase. From Biochemical Curiosity to Physiological/Pathophysiological Significance. Journal of Lipid Research
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