John R. Falck
Affiliations: | University of Texas Southwestern Medical Center, Dallas, TX, United States |
Area:
Biochemistry, Medicinal chemistry, Organometallics, Natural products chemistryWebsite:
http://profiles.utsouthwestern.edu/profile/12144/j-falck.htmlGoogle:
"John R. Falck"Bio:
(born 1948)
http://dgr.rints.com/pdf_2009/d0004877.pdf
Mean distance: (not calculated yet)
Parents
Sign in to add mentorLarry L. Miller | grad student | 1973 | Colorado State |
Elias James Corey | post-doc | 1975-1979 | Harvard |
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Publications
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Gawrys O, Husková Z, Baranowska I, et al. (2020) Combined treatment with epoxyeicosatrienoic acid analog and 20-hydroxyeicosatetraenoic acid antagonist provides substantial hypotensive effect in spontaneously hypertensive rats. Journal of Hypertension |
Guo Z, Lei J, Wu S, et al. (2020) Abstract 4372: Metformin inhibits nuclear localization of estrogen receptor alpha in breast cancer cells, in part, by inhibition of CYP-mediated epoxyeicosatrienoic acid (EET) biosynthesis Epidemiology. 80: 4372-4372 |
Walkowska A, Sadowski J, Cervenka L, et al. (2020) Acute hypotensive effect of EET‐A, a stable analog of epoxyeicosatrienic acid (EET), in spontaneously hypertensive rats: dependence on endogenous EETs activity The Faseb Journal. 34: 1-1 |
Gawrys O, Walkowska A, Kompanowska-Jezierska E, et al. (2020) Effective Antihypertensive Treatment with Epoxyeicosatrienoic Acid Analog (EET‐A) and 20‐HETE Antagonist (AAA) of Spontaneously Hypertensive Rats (SHR) The Faseb Journal. 34: 1-1 |
Adebesin AM, Wesser T, Vijaykumar J, et al. (2019) Development of Robust 17(R),18(S)-Epoxyeicosatetraenoic Acid (17,18-EEQ) Analogs as Potential Clinical Antiarrhythmic Agents. Journal of Medicinal Chemistry |
Dakarapu R, Errabelli R, Manthati VL, et al. (2019) 19-Hydroxyeicosatetraenoic acid analogs: Antagonism of 20-hydroxyeicosatetraenoic acid-induced vascular sensitization and hypertension. Bioorganic & Medicinal Chemistry Letters. 126616 |
Hoff U, Bubalo G, Fechner M, et al. (2019) A synthetic epoxyeicosatrienoic acid analog prevents the initiation of ischemic acute kidney injury. Acta Physiologica (Oxford, England). e13297 |
Chen L, Tang S, Zhang FF, et al. (2019) CYP4A/20-HETE Regulates Ischemia-induced Neovascularization via Its Actions on Endothelial Progenitor and Preexisting Endothelial Cells. American Journal of Physiology. Heart and Circulatory Physiology |
Song CY, Shin JS, Lew J, et al. (2019) Abstract P2029: Cytochrome P450 (CYP) 1B1-Estradiol Metabolite 2-Methoxyestradiol Protects Against Angiotensin II-induced Hypertension By Inhibiting CYP4A1 Expression 20-Hydroxyeicosatetraenoic Acid (20-HETE) Production In The Female Mice Hypertension. 74 |
Capdevila JH, Falck JR. (2018) The Arachidonic Acid Monooxygenase. From Biochemical Curiosity to Physiological/Pathophysiological Significance. Journal of Lipid Research |