Irem Ozkan-Dagliyan
Affiliations: | Department of Pharmacology | University of North Carolina, Chapel Hill, Chapel Hill, NC |
Area:
Cancer biologyGoogle:
"Irem Ozkan-Dagliyan"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Channing J. Der | grad student | University of North Carolina at Chapel Hill School of Medicine (Cell Biology Tree) | |
| Aziz Sancar | research scientist | University of North Carolina at Chapel Hill School of Medicine |
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Publications
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| Goodwin CM, Waters AM, Klomp JE, et al. (2022) Combination Therapies with CDK4/6 Inhibitors to Treat KRAS-mutant Pancreatic Cancer. Cancer Research |
| Diehl JN, Hibshman PS, Ozkan-Dagliyan I, et al. (2021) Targeting the ERK mitogen-activated protein kinase cascade for the treatment of KRAS-mutant pancreatic cancer. Advances in Cancer Research. 153: 101-130 |
| Ozkan-Dagliyan I, Diehl JN, George SD, et al. (2020) Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers. Cell Reports. 31: 107764 |
| Vaseva AV, Blake DR, Gilbert TSK, et al. (2018) KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism. Cancer Cell. 34: 807-822.e7 |
| Dagliyan O, Krokhotin A, Ozkan-Dagliyan I, et al. (2018) Computational design of chemogenetic and optogenetic split proteins. Nature Communications. 9: 4042 |
| Waters AM, Ozkan-Dagliyan I, Vaseva AV, et al. (2017) Evaluation of the selectivity and sensitivity of isoform- and mutation-specific RAS antibodies. Science Signaling. 10 |
| Ye R, Selby CP, Chiou YY, et al. (2014) Dual modes of CLOCK:BMAL1 inhibition mediated by Cryptochrome and Period proteins in the mammalian circadian clock. Genes & Development. 28: 1989-98 |
| Ozkan-Dagliyan I, Chiou YY, Ye R, et al. (2013) Formation of Arabidopsis Cryptochrome 2 photobodies in mammalian nuclei: application as an optogenetic DNA damage checkpoint switch. The Journal of Biological Chemistry. 288: 23244-51 |