Alexander Heckel

Affiliations: 
Goethe University, Frankfurt am Main 
Area:
optochemical biology
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"Alexander Heckel"
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Parents

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Richard R. Schmidt research assistant 1997-1997 University of Constance
 (diploma thesis)
Dieter Seebach grad student 1997-2001 ETH Zürich
 (PhD student)
Peter B. Dervan post-doc 2001-2003 Caltech
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Publications

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Müller P, Seyfried P, Frühauf A, et al. (2019) Phosphodiester photo-tethers for the (multi-)cyclic conformational caging of oligonucleotides. Methods in Enzymology. 624: 89-111
Seyfried P, Heinz M, Pintér G, et al. (2018) Optimal destabilization of DNA double strands by single-nucleobase caging. Chemistry (Weinheim An Der Bergstrasse, Germany)
Reinfelds M, von Cosel J, Falahati K, et al. (2018) A new photocage derived from fluorene. Chemistry (Weinheim An Der Bergstrasse, Germany)
Grebenovsky N, Goldau T, Bolte M, et al. (2018) Light Regulation of DNA Minicircle Dimerization by Utilizing Azobenzene C-Nucleosides. Chemistry (Weinheim An Der Bergstrasse, Germany)
Weyel XMM, Fichte MAH, Heckel A. (2017) A Two-Photon-Photocleavable Linker for Triggering Light-Induced Strand Breaks in Oligonucleotides. Acs Chemical Biology
Meyer A, Slanina T, Heckel A, et al. (2017) Metal ion coupled consecutive photoinduced electron transfer generates strong reduction potentials from visible light. Chemistry (Weinheim An Der Bergstrasse, Germany)
Seyfried P, Eiden L, Grebenovsky N, et al. (2016) Photo-Tethers for the (Multi-)Cyclic, Conformational Caging of Long Oligonucleotides. Angewandte Chemie (International Ed. in English)
Goldau T, Murayama K, Brieke C, et al. (2015) Azobenzene C-Nucleosides for Photocontrolled Hybridization of DNA at Room Temperature. Chemistry (Weinheim An Der Bergstrasse, Germany)
Slanina T, Šebej P, Heckel A, et al. (2015) Caged Fluoride: Photochemistry and Applications of 4-Hydroxyphenacyl Fluoride. Organic Letters. 17: 4814-7
Steinert HS, Schäfer F, Jonker HR, et al. (2014) Influence of the absolute configuration of npe-caged cytosine on DNA single base pair stability. Angewandte Chemie (International Ed. in English). 53: 1072-5
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