David Frederick Stern
Affiliations: | 1988- | Pathology | Yale University, New Haven, CT |
Area:
Receptors and Signal TransductionWebsite:
http://bbs.yale.edu/people/df_stern.profileGoogle:
"David Frederick Stern"Bio:
Parents
Sign in to add mentorJohn J. Holland | grad student | 1983 | UCSD | |
(Multiplication of the avian coronavirus infectious bronchitis virus.) | ||||
Bartholomew M. Sefton | grad student | 1983 | UCSD (Cell Biology Tree) | |
Robert A. Weinberg | post-doc | 1983 | Whitehead Institute for Biomedical Research (Chemistry Tree) |
Children
Sign in to add traineePan Zheng | grad student | Yale | |
David S. Fay | grad student | 1995 | Yale (Cell Biology Tree) |
Dhara N. Amin | grad student | 2003 | Yale |
Nianhan J. Ma | grad student | 2008 | Yale |
Jerrica L. Breindel | grad student | 2012 | Yale |
Kathryn A. Tworkoski | grad student | 2013 | Yale |
David J. Riese | post-doc | 1993-1997 | Yale (Chemistry Tree) |
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Publications
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Gale M, Li Y, Cao J, et al. (2019) Acquired resistance to HER2-targeted therapies creates vulnerability to ATP synthase inhibition. Cancer Research |
Colavito SA, Platt JT, Held MA, et al. (2019) Combinatorial drug screening of mammary cells with induced mesenchymal transformation to identify drug combinations for triple-negative breast cancer. Oncotarget. 10: 4822-4839 |
Theodosakis N, Langdon CG, Micevic G, et al. (2018) Inhibition of isoprenylation synergizes with MAPK blockade to prevent growth in treatment-resistant melanoma, colorectal, and lung cancer. Pigment Cell & Melanoma Research |
Stern DF. (2018) Keeping Tumors Out of the MAPK Fitness Zone. Cancer Discovery. 8: 20-23 |
Klein MI, Stern DF, Zhao H. (2017) GRAPE: a pathway template method to characterize tissue-specific functionality from gene expression profiles. Bmc Bioinformatics. 18: 317 |
Theodosakis N, Micevic G, Langdon CG, et al. (2017) p90RSK blockade inhibits dual BRAF and MEK inhibitor-resistant melanoma by targeting protein synthesis. The Journal of Investigative Dermatology |
Langdon CG, Platt JT, Means RE, et al. (2017) Combinatorial screening of pancreatic adenocarcinoma reveals sensitivity to drug combinations including bromodomain inhibitor plus neddylation inhibitor. Molecular Cancer Therapeutics |
Wali VB, Langdon CG, Held MA, et al. (2016) Systematic drug screening identifies tractable targeted combination therapies in triple-negative breast cancer. Cancer Research |
Jeong J, VanHouten JN, Dann P, et al. (2016) PMCA2 regulates HER2 protein kinase localization and signaling and promotes HER2-mediated breast cancer. Proceedings of the National Academy of Sciences of the United States of America |
Haskins JW, Zhang S, Means RE, et al. (2015) Neuregulin-activated ERBB4 induces the SREBP-2 cholesterol biosynthetic pathway and increases low-density lipoprotein uptake. Science Signaling. 8: ra111 |