Christopher Ott
Affiliations: | Massachusetts General Hospital, Boston, MA |
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Takahashi M, Chong HB, Zhang S, et al. (2023) DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Biorxiv : the Preprint Server For Biology |
Zhang Y, Remillard D, Onubogu U, et al. (2023) Collateral lethality between HDAC1 and HDAC2 exploits cancer-specific NuRD complex vulnerabilities. Nature Structural & Molecular Biology |
Isozaki H, Sakhtemani R, Abbasi A, et al. (2023) Therapy-induced APOBEC3A drives evolution of persistent cancer cells. Nature |
de Matos Simoes R, Shirasaki R, Downey-Kopyscinski SL, et al. (2023) Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias. Nature Cancer. 4: 754-773 |
Bishop TR, Subramanian C, Bilotta EM, et al. (2023) Acetyl-CoA biosynthesis drives resistance to histone acetyltransferase inhibition. Nature Chemical Biology |
Gill T, Wang H, Bandaru R, et al. (2021) Selective targeting of MYC mRNA by stabilized antisense oligonucleotides. Oncogene |
Kong W, Dimitri A, Wang W, et al. (2021) BET bromodomain protein inhibition reverses chimeric antigen receptor extinction and reinvigorates exhausted T cells in chronic lymphocytic leukemia. The Journal of Clinical Investigation. 131 |
Lazarian G, Yin S, Ten Hacken E, et al. (2021) A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation. Cancer Cell. 39: 380-393.e8 |
Koduri V, Duplaquet L, Lampson BL, et al. (2021) Targeting oncoproteins with a positive selection assay for protein degraders. Science Advances. 7 |
Shirasaki R, Matthews GM, Gandolfi S, et al. (2021) Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins. Cell Reports. 34: 108532 |