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Ian D. Simon, Ph.D.

Affiliations: 
2008 Yale University, New Haven, CT 
Area:
Microbiology Biology
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John Kenneth Rose grad student 2008 Yale
 (Replication and persistence of VSV-based vaccine vectors in an animal model.)

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Simon ID, van Rooijen N, Rose JK. (2010) Vesicular stomatitis virus genomic RNA persists in vivo in the absence of viral replication. Journal of Virology. 84: 3280-6
Van Rompay KK, Abel K, Earl P, et al. (2010) Immunogenicity of viral vector, prime-boost SIV vaccine regimens in infant rhesus macaques: attenuated vesicular stomatitis virus (VSV) and modified vaccinia Ankara (MVA) recombinant SIV vaccines compared to live-attenuated SIV. Vaccine. 28: 1481-92
Wollmann G, Rogulin V, Simon I, et al. (2010) Some attenuated variants of vesicular stomatitis virus show enhanced oncolytic activity against human glioblastoma cells relative to normal brain cells. Journal of Virology. 84: 1563-73
van den Pol AN, Ozduman K, Wollmann G, et al. (2009) Viral strategies for studying the brain, including a replication-restricted self-amplifying delta-G vesicular stomatis virus that rapidly expresses transgenes in brain and can generate a multicolor golgi-like expression. The Journal of Comparative Neurology. 516: 456-81
Kapadia SU, Simon ID, Rose JK. (2008) SARS vaccine based on a replication-defective recombinant vesicular stomatitis virus is more potent than one based on a replication-competent vector. Virology. 376: 165-72
Simon ID, Publicover J, Rose JK. (2007) Replication and propagation of attenuated vesicular stomatitis virus vectors in vivo: vector spread correlates with induction of immune responses and persistence of genomic RNA. Journal of Virology. 81: 2078-82
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