Jeffrey A Pleiss

Affiliations: 
Cornell University, Ithaca, NY, United States 
Area:
pre-mRNA splicing
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"Jeffrey Pleiss"
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Parents

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Olke C. Uhlenbeck grad student 1993-2000 CU Boulder
Christine Guthrie post-doc 2001-2007 UCSF
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Publications

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Yang K, Islas N, Jewell S, et al. (2024) Machine learning-optimized targeted detection of alternative splicing. Biorxiv : the Preprint Server For Biology
Downs SR, Grace B, Pleiss JA. (2024) Decoding branch points and unlocking splicing secrets. Nature Structural & Molecular Biology
Dwyer ZW, Pleiss JA. (2023) The problem of selection bias in studies of pre-mRNA splicing. Nature Communications. 14: 1966
Gildea MA, Dwyer ZW, Pleiss JA. (2022) Transcript-specific determinants of pre-mRNA splicing revealed through in vivo kinetic analyses of the 1 and 2 chemical steps. Molecular Cell
Williams JA, Dwyer Z, Fair B, et al. (2020) The Search for Novel Splicing Factors: Mapping Mutations in a Temperature‐Sensitive Schizosaccharomyces pombe Library The Faseb Journal. 34: 1-1
Gildea MA, Dwyer ZW, Pleiss JA. (2019) Multiplexed Primer Extension sequencing: a targeted RNA-seq method that enables high-precision quantitation of mRNA splicing isoforms and rare pre-mRNA splicing intermediates. Methods (San Diego, Calif.)
Xu H, Fair BJ, Dwyer ZW, et al. (2019) Detection of splice isoforms and rare intermediates using multiplexed primer extension sequencing. Nature Methods. 16: 55-58
Thakran P, Pandit PA, Datta S, et al. (2017) Sde2 is an intron-specific pre-mRNA splicing regulator activated by ubiquitin-like processing. The Embo Journal
Yeh CS, Chang SL, Chen JH, et al. (2017) The conserved AU dinucleotide at the 5' end of nascent U1 snRNA is optimized for the interaction with nuclear cap-binding-complex. Nucleic Acids Research. 45: 9679-9693
Mayerle M, Raghavan M, Ledoux S, et al. (2017) Structural toggle in the RNaseH domain of Prp8 helps balance splicing fidelity and catalytic efficiency. Proceedings of the National Academy of Sciences of the United States of America
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