Sarah E. Huff
Affiliations: | 2012-2017 | Case Western Reserve University, Cleveland Heights, OH, United States |
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Parents
Sign in to add mentor| Rajesh Viswanathan | grad student | 2012-2017 | Case Western | |
| (Non - Nucleoside Modulators of Human Ribonucleotide Reductases as Novel Chemotherapeutic Agents) | ||||
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| Zhu Z, Tang R, Huff S, et al. (2023) Small-molecule PTPN2 Inhibitors Sensitize Resistant Melanoma to Anti-PD-1 Immunotherapy. Cancer Research Communications. 3: 119-129 |
| Huff S, Kummetha IR, Zhang L, et al. (2022) Rational Design and Optimization of mA-RNA Demethylase FTO Inhibitors as Anticancer Agents. Journal of Medicinal Chemistry |
| Huff SE, Winter JM, Dealwis CG. (2022) Inhibitors of the Cancer Target Ribonucleotide Reductase, Past and Present. Biomolecules. 12 |
| Huff S, Kummetha IR, Tiwari SK, et al. (2021) Discovery and Mechanism of SARS-CoV-2 Main Protease Inhibitors. Journal of Medicinal Chemistry |
| Huff S, Tiwari SK, Gonzalez GM, et al. (2021) mA-RNA Demethylase FTO Inhibitors Impair Self-Renewal in Glioblastoma Stem Cells. Acs Chemical Biology |
| Li N, Kang Y, Wang L, et al. (2020) ALKBH5 regulates anti-PD-1 therapy response by modulating lactate and suppressive immune cell accumulation in tumor microenvironment. Proceedings of the National Academy of Sciences of the United States of America |
| Sharkey M, Sharova N, Mohammed I, et al. (2019) HIV-1 Escape from Small-Molecule Antagonism of Vif. Mbio. 10 |
| Huff SE, Mohammed FA, Yang M, et al. (2017) Structure-Guided Synthesis and Mechanistic Studies Reveal Sweetspots on Naphthyl Salicyl Hydrazone Scaffold as Non-Nucleosidic Competitive, Reversible Inhibitors of Human Ribonucleotide Reductase. Journal of Medicinal Chemistry |
| Ahmad MF, Alam I, Huff SE, et al. (2017) Potent competitive inhibition of human ribonucleotide reductase by a nonnucleoside small molecule. Proceedings of the National Academy of Sciences of the United States of America |
| Ahmad MF, Huff SE, Pink J, et al. (2015) Identification of non-nucleoside human ribonucleotide reductase modulators. Journal of Medicinal Chemistry |