Melvin V. Simpson

Affiliations: 
1967 Biochemistry Dartmouth University, Hanover, NH, United States 
 1967- Biochemistry Stony Brook University, Stony Brook, NY, United States 
Area:
Mitochondrial DNA and its replication; conformational changes in ribosomes related to function; biochemistry of memory, using split brain systems.
Website:
https://www.stonybrook.edu/commcms/biochem/about-us/history.php
Google:
"Melvin V. Simpson"
Bio:

http://www.jbc.org/content/182/1/81.full.pdf
http://www.jbc.org/content/182/1/91.full.pdf

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Parents

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Harold Tarver grad student 1949 UC Berkeley
 (Studies in protein synthesis using labeled amino acids.)

Children

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Alfred G. Gilman research assistant 1962 Yale
Maurille J. Fournier grad student 1968 Dartmouth University (Cell Biology Tree)
Frank J. Castora post-doc 1976-1981 SUNY Stony Brook
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Publications

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Keilbaugh SA, Hobbs GA, Simpson MV. (1997) Effect of 2',3'-dideoxycytidine on oxidative phosphorylation in the PC12 cell, a neuronal model. Biochemical Pharmacology. 53: 1485-92
Hobbs GA, Keilbaugh SA, Rief PM, et al. (1995) Cellular targets of 3'-azido-3'-deoxythymidine: an early (non-delayed) effect on oxidative phosphorylation. Biochemical Pharmacology. 50: 381-90
Ghazala S, Ramaswamy H, Smith J, et al. (1995) Thermal process simulations for sous vide processing of fish and meat foods Food Research International. 28: 117-122
Barile M, Valenti D, Hobbs GA, et al. (1994) Mechanisms of toxicity of 3'-azido-3'-deoxythymidine. Its interaction with adenylate kinase. Biochemical Pharmacology. 48: 1405-12
Keilbaugh SA, Hobbs GA, Simpson MV. (1993) Anti-human immunodeficiency virus type 1 therapy and peripheral neuropathy: prevention of 2',3'-dideoxycytidine toxicity in PC12 cells, a neuronal model, by uridine and pyruvate. Molecular Pharmacology. 44: 702-6
Hobbs GA, Keilbaugh SA, Simpson MV. (1992) The Friend murine erythroleukemia cell, a model system for studying the association between bone marrow toxicity induced by 3'-azido-3'-dideoxythymidine and dideoxynucleoside inhibition of mtDNA replication. Biochemical Pharmacology. 43: 1397-1400
Phillip LE, Simpson MV. (1992) Differentiation of the effects of protein status and acid-base balance on the appetite of sheep for lucerne silage The Journal of Agricultural Science. 118: 249-257
Keilbaugh SA, Prusoff WH, Simpson MV. (1991) The pc12 cell as a model for studies of the mechanism of induction of peripheral neuropathy by anti-HIV-1 dideoxynucleoside analogs Biochemical Pharmacology. 42: R5-R8
Simpson M, Smith J, Ramaswamy H, et al. (1991) Thermal Kinetic Studies of Streptococcus Faecium in Minimally Processed Sous Vide Products Canadian Institute of Food Science and Technology Journal. 24: 193
SIMPSON B, SIMPSON M, Haard N. (1990) Properties of Trypsin from the Pyloric Ceca of Atlantic Cod (Gadus morhua) Journal of Food Science. 55: 959-961
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