Richard T. Eastman

Affiliations: 
2003- Pathobiology University of Washington, Seattle, Seattle, WA 
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Calit J, Prajapati SK, Benavente ED, et al. (2024) Pyrimidine Azepine Targets the Complex and Displays Multistage Antimalarial Activity. Jacs Au. 4: 3942-3952
Calit J, Araújo JE, Deng B, et al. (2023) Novel Transmission-Blocking Antimalarials Identified by High-Throughput Screening of Plasmodium berghei Ookluc. Antimicrobial Agents and Chemotherapy. e0146522
Singh BK, Zhang C, Wu J, et al. (2023) A Plasmodium falciparum RING Finger E3 Ubiquitin Ligase Modifies the Roles of PfMDR1 and PfCRT in Parasite Drug Responses. Antimicrobial Agents and Chemotherapy. e0082122
Le Manach C, Dam J, Woodland JG, et al. (2021) Identification and Profiling of a Novel Diazaspiro[3.4]octane Chemical Series Active against Multiple Stages of the Human Malaria Parasite and Optimization Efforts. Journal of Medicinal Chemistry
Dorjsuren D, Eastman RT, Wicht KJ, et al. (2021) Chemoprotective antimalarials identified through quantitative high-throughput screening of Plasmodium blood and liver stage parasites. Scientific Reports. 11: 2121
Ansbro MR, Itkin Z, Chen L, et al. (2020) Modulation of Triple Artemisinin-Based Combination Therapy Pharmacodynamics by Genotype. Acs Pharmacology & Translational Science. 3: 1144-1157
Sá JM, Kaslow SR, Moraes Barros RR, et al. (2019) Plasmodium vivax chloroquine resistance links to pvcrt transcription in a genetic cross. Nature Communications. 10: 4300
Sá JM, Kaslow SR, Krause MA, et al. (2018) Artemisinin resistance phenotypes and K13 inheritance in a cross and model. Proceedings of the National Academy of Sciences of the United States of America
Breglio KF, Amato R, Eastman R, et al. (2018) A single nucleotide polymorphism in the Plasmodium falciparum atg18 gene associates with artemisinin resistance and confers enhanced parasite survival under nutrient deprivation. Malaria Journal. 17: 391
Mason DJ, Eastman RT, Lewis RPI, et al. (2018) Using Machine Learning to Predict Synergistic Antimalarial Compound Combinations With Novel Structures. Frontiers in Pharmacology. 9: 1096
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