Richard T. Eastman
Affiliations: | 2003- | Pathobiology | University of Washington, Seattle, Seattle, WA |
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Calit J, Prajapati SK, Benavente ED, et al. (2024) Pyrimidine Azepine Targets the Complex and Displays Multistage Antimalarial Activity. Jacs Au. 4: 3942-3952 |
Calit J, Araújo JE, Deng B, et al. (2023) Novel Transmission-Blocking Antimalarials Identified by High-Throughput Screening of Plasmodium berghei Ookluc. Antimicrobial Agents and Chemotherapy. e0146522 |
Singh BK, Zhang C, Wu J, et al. (2023) A Plasmodium falciparum RING Finger E3 Ubiquitin Ligase Modifies the Roles of PfMDR1 and PfCRT in Parasite Drug Responses. Antimicrobial Agents and Chemotherapy. e0082122 |
Le Manach C, Dam J, Woodland JG, et al. (2021) Identification and Profiling of a Novel Diazaspiro[3.4]octane Chemical Series Active against Multiple Stages of the Human Malaria Parasite and Optimization Efforts. Journal of Medicinal Chemistry |
Dorjsuren D, Eastman RT, Wicht KJ, et al. (2021) Chemoprotective antimalarials identified through quantitative high-throughput screening of Plasmodium blood and liver stage parasites. Scientific Reports. 11: 2121 |
Ansbro MR, Itkin Z, Chen L, et al. (2020) Modulation of Triple Artemisinin-Based Combination Therapy Pharmacodynamics by Genotype. Acs Pharmacology & Translational Science. 3: 1144-1157 |
Sá JM, Kaslow SR, Moraes Barros RR, et al. (2019) Plasmodium vivax chloroquine resistance links to pvcrt transcription in a genetic cross. Nature Communications. 10: 4300 |
Sá JM, Kaslow SR, Krause MA, et al. (2018) Artemisinin resistance phenotypes and K13 inheritance in a cross and model. Proceedings of the National Academy of Sciences of the United States of America |
Breglio KF, Amato R, Eastman R, et al. (2018) A single nucleotide polymorphism in the Plasmodium falciparum atg18 gene associates with artemisinin resistance and confers enhanced parasite survival under nutrient deprivation. Malaria Journal. 17: 391 |
Mason DJ, Eastman RT, Lewis RPI, et al. (2018) Using Machine Learning to Predict Synergistic Antimalarial Compound Combinations With Novel Structures. Frontiers in Pharmacology. 9: 1096 |