Dennis J. Stuehr

Affiliations: 
Cleveland Clinic Foundation, Cleveland, OH, United States 
Area:
Biochemistry
Website:
https://www.lerner.ccf.org/inflammation-immunity/stuehr/
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"Dennis J. Stuehr"
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Publications

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Dai Y, Stuehr DJ. (2025) JBC-D-24-03305 revision 1 Heme Delivery into Soluble Guanylyl Cyclase Requires a Heme Redox Change and is Regulated by NO and Hsp90 by Distinct Mechanisms. The Journal of Biological Chemistry. 108315
Stuehr D, Jayaram D, Sivaram P, et al. (2024) Heme allocation in eukaryotic cells relies on mitochondrial heme export through FLVCR1b to cytosolic GAPDH. Research Square
Sumi MP, Westcott R, Stuehr E, et al. (2024) Regional variations in allergen-induced airway inflammation correspond to changes in soluble guanylyl cyclase heme and expression of heme oxygenase-1. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 38: e23572
Biswas P, Palazzo J, Schlanger S, et al. (2024) Visualizing mitochondrial heme flow through GAPDH in living cells and its regulation by NO. Redox Biology. 71: 103120
Biswas P, Palazzo J, Schlanger S, et al. (2024) Visualizing Mitochondrial Heme Flow through GAPDH to Targets in Living Cells and its Regulation by NO. Biorxiv : the Preprint Server For Biology
Islam S, Jayaram DT, Biswas P, et al. (2024) Functional Maturation of Cytochromes P4503A4 and 2D6 Relies on GAPDH- and Hsp90-Dependent Heme Allocation. The Journal of Biological Chemistry. 105633
Sumi M, Westcott R, Stuehr E, et al. (2023) Regions of Inflammation in mouse asthma correspond to regions of heme-free soluble guanylyl cyclase and can be tracked by marked expression of heme-oxygenase-1. Biorxiv : the Preprint Server For Biology
Jia J, Arif A, Willard B, et al. (2023) Protection of Extraribosomal RPL13a by GAPDH and Dysregulation by S-Nitrosylation. Molecular Cell. 83: 3941
Stuehr DJ, Biswas P, Dai Y, et al. (2023) A natural heme deficiency exists in biology that allows nitric oxide to control heme protein functions by regulating cellular heme distribution. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. e2300055
Sumi MP, Tupta B, Roychowdhury S, et al. (2023) Hemoglobin resident in the lung epithelium is protective for smooth muscle soluble guanylate cyclase function. Redox Biology. 63: 102717
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