Bradley P. Klemm, Ph.D.
Affiliations: | 2011-2017 | Biological Chemistry | University of Michigan, Ann Arbor, Ann Arbor, MI |
| 2017- | Genome Integrity and Structural Biology Laboratory | National Institute of Environmental Health Sciences (NIEHS), Durham, NC, United States |
Area:
Enzymology, biochemistry, structural biologyGoogle:
"Bradley Klemm"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Carol A. Fierke | grad student | 2012-2017 | University of Michigan |
| Roel M. Schaaper | post-doc | 2017- | National Institute of Environmental Health Sciences (NIEHS) |
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Publications
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| Klemm BP, Singh D, Smith CE, et al. (2022) Mechanism by which T7 bacteriophage protein Gp1.2 inhibits dGTPase. Proceedings of the National Academy of Sciences of the United States of America. 119: e2123092119 |
| Klemm BP, Sikkema AP, Hsu AL, et al. (2022) High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP. The Journal of Biological Chemistry. 102073 |
| Bouvette J, Liu HF, Du X, et al. (2021) Beam image-shift accelerated data acquisition for near-atomic resolution single-particle cryo-electron tomography. Nature Communications. 12: 1957 |
| Klemm BP, Karasik A, Kaitany KJ, et al. (2017) Molecular recognition of pre-tRNA by Arabidopsis protein-only Ribonuclease P. Rna (New York, N.Y.) |
| Klemm BP, Wu N, Chen Y, et al. (2016) The Diversity of Ribonuclease P: Protein and RNA Catalysts with Analogous Biological Functions. Biomolecules. 6 |
| Howard MJ, Karasik A, Klemm BP, et al. (2016) Differential substrate recognition by isozymes of plant protein-only Ribonuclease P. Rna (New York, N.Y.) |
| Howard MJ, Klemm BP, Fierke CA. (2015) Mechanistic Studies Reveal Similar Catalytic Strategies for Phosphodiester Bond Hydrolysis by Protein-only and RNA-dependent Ribonuclease P. The Journal of Biological Chemistry. 290: 13454-64 |
| Howard MJ, Liu X, Lim WH, et al. (2013) RNase P enzymes: divergent scaffolds for a conserved biological reaction. Rna Biology. 10: 909-14 |