Stephan Sieber
Affiliations: | Scripps Research Institute, La Jolla, La Jolla, CA, United States |
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Parents
Sign in to add mentor| Mohamed A. Marahiel | grad student | 2004 | University of Marburg |
| Christopher T. Walsh | grad student | 2004 | Harvard |
| Benjamin F. Cravatt | post-doc | Scripps Institute |
Children
Sign in to add trainee| Malte Gersch | grad student | Technische Universität München | |
| Maximilian Pitscheider | grad student | Technische Universität München | |
| Georg Rudolph | grad student | Technische Universität München | |
| Thomas Böttcher | grad student | 2006-2009 | Ludwig Maximilian University Munich |
| Weining Zhao | grad student | 2012-2016 | Technical University of Munich |
| Megan H. Wright | post-doc | Technische Universität München | |
| Thomas Böttcher | post-doc | 2010-2010 | Technical University of Munich |
| Weining Zhao | post-doc | 2016-2018 | Technical University of Munich |
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Publications
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| Schum D, Elsen FAV, Ruddell S, et al. (2024) Screening Privileged Alkyl Guanidinium Motifs under Host-Mimicking Conditions Reveals a Novel Antibiotic with an Unconventional Mode of Action. Jacs Au. 4: 3125-3134 |
| Scharnow AM, Solinski AE, Rowe S, et al. (2024) In Situ Biofilm Affinity-Based Protein Profiling Identifies the Streptococcal Hydrolase GbpB as the Target of a Carolacton-Inspired Chemical Probe. Journal of the American Chemical Society. 146: 23449-23456 |
| Geißler A, Junca H, Kany AM, et al. (2024) Isocyanides inhibit bacterial pathogens by covalent targeting of essential metabolic enzymes. Chemical Science. 15: 11946-11955 |
| Chen SY, Fiedler MK, Gronauer TF, et al. (2024) Unraveling the mechanism of small molecule induced activation of Staphylococcus aureus signal peptidase IB. Communications Biology. 7: 895 |
| Ruddell SA, Mostert D, Sieber SA. (2024) Target identification of usnic acid in bacterial and human cells. Rsc Chemical Biology. 5: 617-621 |
| Mostert D, Bubeneck WA, Rauh T, et al. (2024) Pronucleotide Probes Reveal a Diverging Specificity for AMPylation vs UMPylation of Human and Bacterial Nucleotide Transferases. Biochemistry. 63: 651-659 |
| Weigert Muñoz A, Zhao W, Sieber SA. (2023) Monitoring host-pathogen interactions using chemical proteomics. Rsc Chemical Biology. 5: 73-89 |
| Illigmann A, Vielberg MT, Lakemeyer M, et al. (2023) Structure of Staphylococcus aureus ClpP Bound to the Covalent Active Site Inhibitor Cystargolide A. Angewandte Chemie (International Ed. in English). e202314028 |
| Dienemann JN, Chen SY, Hitzenberger M, et al. (2023) A Chemical Proteomic Strategy Reveals Inhibitors of Lipoate Salvage in Bacteria and Parasites. Angewandte Chemie (International Ed. in English). e202304533 |
| Wilkinson IVL, Castro-Falcón G, Roda-Serrat MC, et al. (2022) The Cyanobacterial "Nutraceutical" Phycocyanobilin Inhibits Cysteine Protease Legumain. Chembiochem : a European Journal of Chemical Biology. e202200455 |