Stephan Sieber

Scripps Research Institute, La Jolla, La Jolla, CA, United States 
"Stephan Sieber"
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Morimoto K, Krahn D, Kaschani F, et al. (2022) Broad-range metalloprotease profiling in plants uncovers immunity provided by defence-related metalloenzyme. The New Phytologist
Wilkinson IVL, Pfanzelt M, Sieber SA. (2022) Functionalised Cofactor Mimics for Interactome Discovery and Beyond. Angewandte Chemie (International Ed. in English)
Pfanzelt M, Maher TE, Absmeier RM, et al. (2022) Tailored Pyridoxal Probes Unravel Novel Cofactor-Dependent Targets and Antibiotic Hits in Critical Bacterial Pathogens. Angewandte Chemie (International Ed. in English)
Hübner I, Shapiro JA, Hoßmann J, et al. (2021) Broad Spectrum Antibiotic Xanthocillin X Effectively Kills Dysregulation of Heme Biosynthesis. Acs Central Science. 7: 488-498
Macsics R, Hackl MW, Fetzer C, et al. (2020) Comparative Target Analysis of Chlorinated Biphenyl Antimicrobials Highlights MenG as Molecular Target of Triclocarban. Applied and Environmental Microbiology
Lee KM, Le P, Sieber SA, et al. (2020) Degrasyn exhibits antibiotic activity against multi-resistant Staphylococcus aureus by modifying several essential cysteines. Chemical Communications (Cambridge, England)
Le P, Kunold E, Macsics R, et al. (2019) Repurposing human kinase inhibitors to create an antibiotic active against drug-resistant Staphylococcus aureus, persisters and biofilms. Nature Chemistry
Zhao W, Cross AR, Crowe-McAuliffe C, et al. (2019) The natural product elegaphenone potentiates antibiotic effects against Pseudomonas aeruginosa. Angewandte Chemie (International Ed. in English)
Falcón García C, Stangl F, Götz A, et al. (2018) Topographical alterations render bacterial biofilms susceptible to chemical and mechanical stress. Biomaterials Science. 7: 220-232
Hoegl A, Nodwell MB, Kirsch VC, et al. (2018) Mining the cellular inventory of pyridoxal phosphate-dependent enzymes with functionalized cofactor mimics. Nature Chemistry
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