Alexander J. Federation

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2016-2019 Genome Sciences University of Washington, Seattle, Seattle, WA 
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Federation AJ, Nandakumar V, Searle BC, et al. (2020) Highly Parallel Quantification and Compartment Localization of Transcription Factors and Nuclear Proteins. Cell Reports. 30: 2463-2471.e5
Lazarchuk P, Hernandez-Villanueva J, Pavlova MN, et al. (2020) Mutual Balance of Histone Deacetylases 1 and 2 and the Acetyl Reader ATAD2 Regulates the Level of Acetylation of Histone H4 on Nascent Chromatin of Human Cells. Molecular and Cellular Biology. 40
Ott CJ, Federation AJ, Schwartz LS, et al. (2018) Enhancer Architecture and Essential Core Regulatory Circuitry of Chronic Lymphocytic Leukemia. Cancer Cell
Zhang Y, Federation AJ, Kim S, et al. (2018) Targeting nuclear receptor NR4A1-dependent adipocyte progenitor quiescence promotes metabolic adaptation to obesity. The Journal of Clinical Investigation
Brown JD, Feldman ZB, Doherty SP, et al. (2018) BET bromodomain proteins regulate enhancer function during adipogenesis. Proceedings of the National Academy of Sciences of the United States of America
Mack SC, Pajtler KW, Chavez L, et al. (2017) Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling. Nature
Cheng J, Park DE, Berrios C, et al. (2017) Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis. Plos Pathogens. 13: e1006668
Zhang H, Qi J, Reyes JM, et al. (2016) Oncogenic deregulation of EZH2 as an opportunity for targeted therapy in lung cancer. Cancer Discovery
Saint-André V, Federation AJ, Lin CY, et al. (2016) Models of human core transcriptional regulatory circuitries. Genome Research
Bandopadhayay P, Ramkissoon LA, Jain P, et al. (2016) MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism. Nature Genetics
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