Athri D. Rathnayake
Affiliations: | 2015-2020 | Chemistry | Wichita State University, Wichita, KS, United States |
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Publications
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Dampalla CS, Nguyen HN, Rathnayake AD, et al. (2022) Broad-Spectrum Cyclopropane-Based Inhibitors of Coronavirus 3C-like Proteases: Biochemical, Structural, and Virological Studies. Acs Pharmacology & Translational Science. 6: 181-194 |
Dampalla CS, Rathnayake AD, Galasiti Kankanamalage AC, et al. (2022) Structure-Guided Design of Potent Spirocyclic Inhibitors of Severe Acute Respiratory Syndrome Coronavirus-2 3C-like Protease. Journal of Medicinal Chemistry. 65: 7818-7832 |
Dampalla CS, Rathnayake AD, Perera KD, et al. (2021) Structure-Guided Design of Potent Inhibitors of SARS-CoV-2 3CL Protease: Structural, Biochemical, and Cell-Based Studies. Journal of Medicinal Chemistry |
Dampalla CS, Kim Y, Bickmeier N, et al. (2021) Structure-Guided Design of Conformationally Constrained Cyclohexane Inhibitors of Severe Acute Respiratory Syndrome Coronavirus-2 3CL Protease. Journal of Medicinal Chemistry |
Rathnayake AD, Kim Y, Dampalla CS, et al. (2020) Structure-Guided Optimization of Dipeptidyl Inhibitors of Norovirus 3CL Protease. Journal of Medicinal Chemistry |
Rathnayake AD, Zheng J, Kim Y, et al. (2020) 3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice. Science Translational Medicine |
Perera KD, Rathnayake AD, Liu H, et al. (2019) Characterization of amino acid substitutions in feline coronavirus 3C-like protease from a cat with feline infectious peritonitis treated with a protease inhibitor. Veterinary Microbiology. 237: 108398 |
Galasiti Kankanamalage AC, Weerawarna PM, Rathnayake AD, et al. (2019) Putative Structural Rearrangements Associated with the Interaction of Macrocyclic Inhibitors with Norovirus 3CL Protease. Proteins |
Chang KO, Kim Y, Lovell S, et al. (2019) Antiviral Drug Discovery: Norovirus Proteases and Development of Inhibitors. Viruses. 11 |
Perera KD, Galasiti Kankanamalage AC, Rathnayake AD, et al. (2018) Protease inhibitors broadly effective against feline, ferret and mink coronaviruses. Antiviral Research |