Macy Sprunger

Affiliations: 
Washington University, Saint Louis, St. Louis, MO 
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"Macy Sprunger"
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Sprunger ML, Jackrel ME. (2024) The role of Matrin-3 in physiology and its dysregulation in disease. Biochemical Society Transactions
Chen S, Puri A, Bell B, et al. (2024) HTRA1 disaggregates α-synuclein amyloid fibrils and converts them into non-toxic and seeding incompetent species. Nature Communications. 15: 2436
Chen S, Puri A, Bell B, et al. (2023) HtrA1 prevents and reverses α-synuclein aggregation, rendering it non-toxic and seeding incompetent. Research Square
Shrimali PC, Chen S, Das A, et al. (2023) Amyloidogenic Propensity of Self-Assembling Peptides and their Adjuvant Potential for use as DNA Vaccines. Acta Biomaterialia
Sprunger ML, Jackrel ME. (2022) Monitoring condensate dynamics in using fluorescence recovery after photobleaching. Star Protocols. 3: 101592
Sprunger ML, Lee K, Sohn BS, et al. (2022) Molecular determinants and modifiers of Matrin-3 toxicity, condensate dynamics, and droplet morphology. Iscience. 25: 103900
Sprunger ML, Jackrel ME. (2021) Prion-Like Proteins in Phase Separation and Their Link to Disease. Biomolecules. 11
Ryan JJ, Sprunger ML, Holthaus K, et al. (2019) Correction: Engineered protein disaggregases mitigate toxicity of aberrant prion-like fusion proteins underlying sarcoma. The Journal of Biological Chemistry. 294: 17707
Sprunger ML, Jackrel ME. (2019) Quality Control in the ER: Misfolded Prohormones Get a Checkup. Molecular Cell. 75: 415-416
Ryan JJ, Sprunger ML, Holthaus K, et al. (2019) Engineered protein disaggregases mitigate toxicity of aberrant prion-like fusion proteins underlying sarcoma. The Journal of Biological Chemistry
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