Yasanandana S. Wijayasinghe, PhD

Affiliations: 
2008- Faculty of Medicine university of kelaniya 
Area:
Biochemistry
Website:
https://medicine.kln.ac.lk/index.php/dr-y-s-wijayasinghe.html
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"Yasanandana Wijayasinghe"
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Parents

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Ronald E. Viola grad student 2014 The University of Toledo
 (Molecular Insights into N-acetylaspartate Metabolism in Canavan Disease)
Tom E. Ellenberger post-doc 2014-2015 Washington University (Cell Biology Tree)
 (Biophysical Characterization of Sirtuin1-Pparg interaction)
BETA: Related publications

Publications

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Poddar NK, Wijayasinghe YS, Viola RE. (2024) Identification of potential pharmacological chaperones that selectively stabilize mutated Aspartoacylases in Canavan disease. Biochimica Et Biophysica Acta. Proteins and Proteomics. 1872: 141043
Ilyas A, Wijayasinghe YS, Khan I, et al. (2022) Implications of trimethylamine N-oxide (TMAO) and Betaine in Human Health: Beyond Being Osmoprotective Compounds. Frontiers in Molecular Biosciences. 9: 964624
Wijayasinghe YS, Bhansali MP, Borkar MR, et al. (2022) A Comprehensive Biological and Synthetic Perspective on 2-Deoxy-d-Glucose (2-DG), A Sweet Molecule with Therapeutic and Diagnostic Potentials. Journal of Medicinal Chemistry. 65: 3706-3728
Wijayasinghe YS, Bhansali P, Viola RE, et al. (2020) Natural Products: A Rich Source of Antiviral Drug Lead Candidates for the Management of COVID-19. Current Pharmaceutical Design
Zhao M, Wijayasinghe YS, Bhansali P, et al. (2015) A surprising range of modified-methionyl S-adenosylmethionine analogues support bacterial growth. Microbiology (Reading, England). 161: 674-82
Wijayasinghe YS, Pavlovsky AG, Viola RE. (2014) Aspartoacylase catalytic deficiency as the cause of Canavan disease: a structural perspective. Biochemistry. 53: 4970-8
Wijayasinghe YS, Blumenthal RM, Viola RE. (2014) Producing proficient methyl donors from alternative substrates of S-adenosylmethionine synthetase. Biochemistry. 53: 1521-6
Zano S, Wijayasinghe YS, Malik R, et al. (2013) Relationship between enzyme properties and disease progression in Canavan disease. Journal of Inherited Metabolic Disease. 36: 1-6
Zano S, Wijayasinghe YS, Malik R, et al. (2012) Erratum to: Relationship between enzyme properties and disease progression in Canavan disease Journal of Inherited Metabolic Disease. 36: 159-160
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