Ludovic Halby
Affiliations: | structural biology and chemistry | Institut Pasteur, Paris, Paris, France |
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| Castillo-Aguilera OO, Depreux P, Halby L, et al. (2025) Design, synthesis and evaluation of pyrimidinobenzylamide and pyrimidinothiophenamide derivatives as inhibitors of DOT1L and related epigenetic targets DNMT3a, PRMT4 and other HMTs. Rsc Medicinal Chemistry |
| Dobrescu I, Hammam E, Dziekan JM, et al. (2023) Eukaryotic Translation Initiation Factor 3 is Stabilized by Quinazoline-Quinoline Bisubstrate Inhibitors. Acs Infectious Diseases |
| Nardella F, Dobrescu I, Hassan H, et al. (2023) Hemisynthetic alkaloids derived from trilobine are antimalarials with sustained activity in multidrug-resistant . Iscience. 26: 105940 |
| Lopez M, Gilbert J, Contreras J, et al. (2022) Inhibitors of DNA Methylation. Advances in Experimental Medicine and Biology. 1389: 471-513 |
| Si Y, Bon C, Barbachowska M, et al. (2022) A novel screening strategy to identify histone methyltransferase inhibitors reveals a crosstalk between DOT1L and CARM1. Rsc Chemical Biology. 3: 456-467 |
| Bon C, Barbachowska M, Djokovic N, et al. (2022) Quinazoline-based analog of adenine as an antidote against MLL-rearranged leukemia cells: synthesis, inhibition assays and docking studies. Future Medicinal Chemistry. 14: 557-570 |
| Miethke M, Pieroni M, Weber T, et al. (2021) Towards the sustainable discovery and development of new antibiotics. Nature Reviews. Chemistry. 5: 726-749 |
| Bon C, Si Y, Pernak M, et al. (2021) Synthesis and Biological Activity of a Cytostatic Inhibitor of MLLr Leukemia Targeting the DOT1L Protein. Molecules (Basel, Switzerland). 26 |
| Miethke M, Pieroni M, Weber T, et al. (2021) Towards the sustainable discovery and development of new antibiotics. Nature Reviews. Chemistry. 1-24 |
| Bon C, Arimondo PB, Halby L. (2021) Direct Synthesis of Allyl Amines with 2-Nitrosulfonamide Derivatives via the Tsuji-Trost Reaction. Chemistryopen. 10: 1166-1169 |