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Gertrude B. Elion

Affiliations: 
Wellcome Research Laboratories 
Website:
http://www.nobelprize.org/nobel_prizes/medicine/laureates/1988/elion-bio.html
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"Gertrude B. Elion"
Bio:

(1918 - 1999)
http://www.annualreviews.org/doi/pdf/10.1146/annurev.pa.33.040193.000245@mednobel.2009.1.issue-1
The Nobel Prize in Physiology or Medicine 1988 was awarded jointly to Sir James W. Black, Gertrude B. Elion and George H. Hitchings for their discoveries of important principles for drug treatment.

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Publications

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Hitchings GH, Elion GB. (2006) Some Aspects Of Immunosuppression Annals of the New York Academy of Sciences. 129: 799-803
Kurtzberg J, Ernst TJ, Keating MJ, et al. (2005) Phase I study of 506U78 administered on a consecutive 5-day schedule in children and adults with refractory hematologic malignancies Journal of Clinical Oncology. 23: 3396-3403
BALIS ME, LEVIN DH, BROWN GB, et al. (2000) The effects of 6-mercaptopurine on Lactobacillus casei. Archives of Biochemistry and Biophysics. 71: 358-66
Patel VJ, Elion GB, Houghton PJ, et al. (2000) Schedule-dependent activity of temozolomide plus CPT-11 against a human central nervous system tumor-derived xenograft. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 6: 4154-7
Castellino RC, Elion GB, Keir ST, et al. (2000) Schedule-dependent activity of irinotecan plus BCNU against malignant glioma xenografts. Cancer Chemotherapy and Pharmacology. 45: 345-9
Elion GB, Furman PA, Fyfe JA, et al. (1999) The selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl) guanine. Reproduced from Proc. Natl. Acad. Sci. USA 74, 5716-5720 (1977) Reviews in Medical Virology. 9: 147-52; discussion 1
Elion GB. (1999) Personal reflections Annals of the New York Academy of Sciences. 869: 16-18
Hanley ML, Elion GB, Colvin OM, et al. (1998) Therapeutic efficacy of vinorelbine against pediatric and adult central nervous system tumors. Cancer Chemotherapy and Pharmacology. 42: 479-82
Coggins CA, Elion GB, Houghton PJ, et al. (1998) Enhancement of irinotecan (CPT-11) activity against central nervous system tumor xenografts by alkylating agents. Cancer Chemotherapy and Pharmacology. 41: 485-90
Hare CB, Elion GB, Colvin OM, et al. (1997) Characterization of the mechanisms of busulfan resistance in a human glioblastoma multiforme xenograft. Cancer Chemotherapy and Pharmacology. 40: 409-14
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