Patrick E MacDonald

Affiliations: 
Pharmacology University of Alberta, Edmonton, Alberta, Canada 
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Kolic J, Sun WG, Cen HH, et al. (2024) Proteomic predictors of individualized nutrient-specific insulin secretion in health and disease. Medrxiv : the Preprint Server For Health Sciences
Lin H, Suzuki K, Smith N, et al. (2024) A role and mechanism for redox sensing by SENP1 in β-cell responses to high fat feeding. Nature Communications. 15: 334
Coykendall VMN, Qian MF, Tellez K, et al. (2023) RFX6 maintains gene expression and function of adult human islet α cells. Diabetes
Moss ND, Wells KL, Theis A, et al. (2023) Modulation of insulin secretion by RBFOX2-mediated alternative splicing. Nature Communications. 14: 7732
Qian MF, Bevacqua RJ, Coykendall VM, et al. (2023) HNF1α maintains pancreatic α and β cell functions in primary human islets. Jci Insight
Chen YC, Taylor AJ, Fulcher JM, et al. (2023) Deletion of carboxypeptidase E in beta cells disrupts proinsulin processing but does not lead to spontaneous development of diabetes in mice. Diabetes
MacDonald PE, Rorsman P. (2023) Metabolic Messengers: glucagon. Nature Metabolism
Mattis KK, Krentz NAJ, Metzendorf C, et al. (2023) Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression. Diabetologia
Rottner AK, Ye Y, Navarro-Guerrero E, et al. (2022) A genome-wide CRISPR screen identifies CALCOCO2 as a regulator of beta cell function influencing type 2 diabetes risk. Nature Genetics
Alghamdi TA, Krentz NAJ, Smith N, et al. (2022) Zmiz1 is required for mature β-cell function and mass expansion upon high fat feeding. Molecular Metabolism. 66: 101621
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