Patrick E MacDonald
Affiliations: | Pharmacology | University of Alberta, Edmonton, Alberta, Canada |
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Publications
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Kolic J, Sun WG, Cen HH, et al. (2024) Proteomic predictors of individualized nutrient-specific insulin secretion in health and disease. Medrxiv : the Preprint Server For Health Sciences |
Lin H, Suzuki K, Smith N, et al. (2024) A role and mechanism for redox sensing by SENP1 in β-cell responses to high fat feeding. Nature Communications. 15: 334 |
Coykendall VMN, Qian MF, Tellez K, et al. (2023) RFX6 maintains gene expression and function of adult human islet α cells. Diabetes |
Moss ND, Wells KL, Theis A, et al. (2023) Modulation of insulin secretion by RBFOX2-mediated alternative splicing. Nature Communications. 14: 7732 |
Qian MF, Bevacqua RJ, Coykendall VM, et al. (2023) HNF1α maintains pancreatic α and β cell functions in primary human islets. Jci Insight |
Chen YC, Taylor AJ, Fulcher JM, et al. (2023) Deletion of carboxypeptidase E in beta cells disrupts proinsulin processing but does not lead to spontaneous development of diabetes in mice. Diabetes |
MacDonald PE, Rorsman P. (2023) Metabolic Messengers: glucagon. Nature Metabolism |
Mattis KK, Krentz NAJ, Metzendorf C, et al. (2023) Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression. Diabetologia |
Rottner AK, Ye Y, Navarro-Guerrero E, et al. (2022) A genome-wide CRISPR screen identifies CALCOCO2 as a regulator of beta cell function influencing type 2 diabetes risk. Nature Genetics |
Alghamdi TA, Krentz NAJ, Smith N, et al. (2022) Zmiz1 is required for mature β-cell function and mass expansion upon high fat feeding. Molecular Metabolism. 66: 101621 |